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Cells | Highly Cited Papers Published in 2024 in the “Autophagy” Section

Cells | Highly Cited Papers Published in 2024 in the “Autophagy” Section

4 December 2025


Macro-autophagy, micro-autophagy, and chaperone-mediated autophagy are lysosomal degradative processes that allow cells to eliminate unwanted or dysfunctional protein/protein complexes, superfluous or damaged organelles, and invading pathogens. In most scenarios, autophagy processes specifically target structures that cells do not want. As a result, they are involved in a multitude of physiological functions and pathological situations. Autophagy is currently one of the fastest-growing research areas in life and medical sciences.

The “Autophagy” Section of Cells (ISSN 2073-4409) aims to be an active part of the international autophagy research community and aims to attract manuscripts detailing the latest cutting-edge research on autophagy across kingdoms.

1. “Bitter Taste Receptor T2R14 and Autophagy Flux in Gingival Epithelial Cells”
by Nisha Singh, Ben Ulmer, Manoj Reddy Medapati, Christine Zhang, Robert J. Schroth, Saeid Ghavami and Prashen Chelikani
Cells 2024, 13(6), 531; https://doi.org/10.3390/cells13060531
Available online: https://www.mdpi.com/2073-4409/13/6/531

2. “TRIM44, a Novel Prognostic Marker, Supports the Survival of Proteasome-Resistant Multiple Myeloma Cells”
by Trung Vu, Yuqin Wang, Annaliese Fowler, Anton Simieou and Nami McCarty
Cells 2024, 13(17), 1431; https://doi.org/10.3390/cells13171431
Available online: https://www.mdpi.com/2073-4409/13/17/1431

3. “Lysosome-Disrupting Agents in Combination with Venetoclax Increase Apoptotic Response in Primary Chronic Lymphocytic Leukemia (CLL) Cells Mediated by Lysosomal Cathepsin D Release and Inhibition of Autophagy”
by Madhumita S. Manivannan, Xiaoyan Yang, Nirav Patel, Anthea Peters, James B. Johnston and Spencer B. Gibson
Cells 2024, 13(12), 1041; https://doi.org/10.3390/cells13121041
Available online: https://www.mdpi.com/2073-4409/13/12/1041

4. “An Intrinsic Host Defense against HSV-1 Relies on the Activation of Xenophagy with the Active Clearance of Autophagic Receptors”
by Camila Pino-Belmar, Rayén Aguilar, Guillermo E. Valenzuela-Nieto, Viviana A. Cavieres, Cristóbal Cerda-Troncoso, Valentina C. Navarrete, Paula Salazar, Patricia V. Burgos, Carola Otth and Hianara A. Bustamante
Cells 2024, 13(15), 1256; https://doi.org/10.3390/cells13151256
Available online: https://www.mdpi.com/2073-4409/13/15/1256

5. “Distinct UPR and Autophagic Functions Define Cell-Specific Responses to Proteotoxic Stress in Microglial and Neuronal Cell Lines”
by Helena Domínguez-Martín, Elena Gavilán, Celia Parrado, Miguel A. Burguillos, Paula Daza and Diego Ruano
Cells 2024, 13(24), 2069; https://doi.org/10.3390/cells13242069
Available online: https://www.mdpi.com/2073-4409/13/24/2069

6. “Molecular Mechanism of Autophagosome–Lysosome Fusion in Mammalian Cells”
by Po-Yuan Ke
Cells 2024, 13(6), 500; https://doi.org/10.3390/cells13060500
Available online: https://www.mdpi.com/2073-4409/13/6/500

7. “The Yin and Yang of Microglia-Derived Extracellular Vesicles in CNS Injury and Diseases”
by Mousumi Ghosh and Damien D. Pearse
Cells 2024, 13(22), 1834; https://doi.org/10.3390/cells13221834
Available online: https://www.mdpi.com/2073-4409/13/22/1834

8. “Molecular Mechanisms of Autophagy Decline during Aging”
by Shaun H. Y. Lim, Malene Hansen and Caroline Kumsta
Cells 2024, 13(16), 1364; https://doi.org/10.3390/cells13161364
Available online: https://www.mdpi.com/2073-4409/13/16/1364