Special Issue "Reoviruses"
Deadline for manuscript submissions: closed (31 December 2020).
Interests: reovirus entry; host responses and cell death
Interests: reoviridae; virus adaptation; oncolytic viruses; protein structure-function relationships; virus assembly; cell signalling in response to virus
Since the fortuitous discovery of reoviruses in the 1950s, these dsRNA icosahedral members of the Reoviridae family have served to understand countless concepts in cell biology, virology, and virus–host interactions in vitro, cell cultures, and animal models. Among the many molecular contributions, research on reoviruses facilitated the discovery of mRNA capping, and the realization that non-enveloped viruses can also encode membrane fusogenic proteins, thus understanding the virus structure, mechanisms of cell attachment, and virus entry. Recent advances in high resolution virus structure determination show remarkable routes of capsid evolution among members of the Reoviridae. In vivo, reoviruses serve as powerful model systems for a better understanding antiviral signaling and virus-induced disease pathogenesis. Most recently, reoviruses provide insight into gut microbe interactions between viruses and bacteria. Reoviruses, as well as reovirus-derived fusogenic proteins, are also being developed into cancer therapies.
Reoviridae diverged into the sedoreovirinae (nonturreted) and spinareovirinae (turreted) subfamilies; each subfamily containing virus members that are pathogenic, or potential tools for beneficial application. Although the reovirus designation generally refers to the orthoreovirus genus, this Special Issue is designed to provide an up-to-date view of the spinareovirinae subfamily in general. With shared evolution, each genus of spinareovirinae offers a strategy to better understand, control, or exploit this subfamily of viruses. This Special Issue invites both general updating reviews on aquareoviruses, coltiviruses, cypoviruses, fijiviruses, orthoreoviruses, idnoreoviruses, dinovernaviruses, oryzaviruses, and mycoreoviruses, as well as reviews and original research articles on specific topics such as evolution, structure–function of specific spinareovirinae proteins, or host–pathogen interactions.
Dr. Pranav Danthi
Dr. Maya Shmulevitz
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Viruses is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- virus attachment
- virus entry
- replication mechanisms
- innate immune responses
- reverse genetics
- virus structure