Special Issue "Hantavirus Research in Finland"
Deadline for manuscript submissions: closed (28 February 2022) | Viewed by 9330
Puumala hantavirus (PUUV) infections are common in Finland, making this country the most endemic area of hantavirus infections per inhabitant. PUUV is the only human pathogenic hantavirus found in this country. The natural reservoir for PUUV is the bank vole (Myodes glareolus). Scientific research on the disease, previously described as nephropathia epidemica, started in Finland in the 1970s and PUUV was discovered in 1980. The structure of PUUV and serological diagnostics have been and are currently studied, as are the epidemiology, risk factors, and immune response of the infection, disease severity biomarkers, and host genetics. Other research topics include the pathogenesis of the main clinical manifestations, capillary leakage, thrombocytopenia, and acute kidney injury (AKI), as well as acute-phase complications and long-term prognosis of the infection. Studies on the pathogenesis and immune response may show the way towards optimal prophylaxis and treatment.
Studies on the dynamics and genetics of PUUV in bank vole populations have also been performed. Finnish scientists have worked together with many collaborators in European, Asian, and American countries. In these projects, hantaviruses other than PUUV have also been studied.
The present Special Issue includes reviews, original articles, and short communications about PUUV infections showing that the research continues actively in Finland.
Prof. Dr. Jukka T. Mustonen
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- Puumala virus
- hantavirus infections
- bank vole