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Review

Central Nervous System and Ocular Manifestations in Puumala Hantavirus Infection

1
Medical Research Center, PEDEGO Research Unit, Department of Ophthalmology, Oulu University Hospital and University of Oulu, 90029 Oulu, Finland
2
Research Unit of Internal Medicine, Department of Internal Medicine, Division of Infectious Diseases, Oulu University and Oulu University Hospital, 90014 Oulu, Finland
3
Research Unit of Biomedicine, University of Oulu, 90029 Oulu, Finland
*
Author to whom correspondence should be addressed.
Academic Editor: Jukka T. Mustonen
Viruses 2021, 13(6), 1040; https://doi.org/10.3390/v13061040
Received: 19 April 2021 / Revised: 26 May 2021 / Accepted: 26 May 2021 / Published: 31 May 2021
(This article belongs to the Special Issue Hantavirus Research in Finland)
Puumala hantavirus (PUUV), carried and spread by the bank vole (Myodes glareolus), causes a mild form of hemorrhagic fever with renal syndrome (HFRS) called nephropathia epidemica (NE). Acute high fever, acute kidney injury (AKI), thrombocytopenia, and hematuria are typical features of this syndrome. In addition, headache, blurred vision, insomnia, vertigo, and nausea are commonly associated with the disease. This review explores the mechanisms and presentations of ocular and central nervous system involvement in acute NE. View Full-Text
Keywords: hantavirus; central nervous system; encephalitis; visual disorders; intraocular pressure; myopic shift hantavirus; central nervous system; encephalitis; visual disorders; intraocular pressure; myopic shift
MDPI and ACS Style

Hautala, N.; Partanen, T.; Kubin, A.-M.; Kauma, H.; Hautala, T. Central Nervous System and Ocular Manifestations in Puumala Hantavirus Infection. Viruses 2021, 13, 1040. https://doi.org/10.3390/v13061040

AMA Style

Hautala N, Partanen T, Kubin A-M, Kauma H, Hautala T. Central Nervous System and Ocular Manifestations in Puumala Hantavirus Infection. Viruses. 2021; 13(6):1040. https://doi.org/10.3390/v13061040

Chicago/Turabian Style

Hautala, Nina, Terhi Partanen, Anna-Maria Kubin, Heikki Kauma, and Timo Hautala. 2021. "Central Nervous System and Ocular Manifestations in Puumala Hantavirus Infection" Viruses 13, no. 6: 1040. https://doi.org/10.3390/v13061040

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