New Aspects of Adenoviral Vaccine Vectors and Adenoviral Gene Therapy

Dear colleagues,

Adenoviruses are commonly used as efficient high-capacity vectors and as excellent gene delivery vehicles. Their applications range from basic molecular research to gene therapy and viral vector vaccines. Adenoviral vectors are currently being used in regenerative and cancer therapies and, most importantly, as vaccines such as in first-generation COVID-19 vaccines. Despite widespread applications and constant progress, various challenges and safety concerns still limit using adenoviral vectors to their full potential. Our Special Issue will publish original research articles and reviews that include, but are not limited to, investigations on (cross-species) adenoviral vector development, viral persistence and genomic integration, adenoviral tissue tropism, and relevant studies on adenoviral biology. Together, this collection of articles will provide new aspects of adenoviral vectors and their applications in vaccine and gene therapy settings.

We’re looking forward to reading your contributions!

Prof. Dr. Thomas Dobner
Dr. Luca Bertzbach
Guest Editors

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