Tackling Viral Resistance—Advances in Mechanisms, Detection, and Control

Dear Colleagues,

The global burden of viral infections represents a critical public health challenge as resistance to antiviral therapies increasingly undermines efforts to control viral diseases. Although antiviral treatments have prevented millions of deaths globally, the emergence of drug resistance, observed across various viruses, including influenza, HIV, and SARS-CoV-2, threatens the effectiveness of current therapeutic options and complicates global response strategies.

This Special Issue will gather new research on mechanisms, detection, and clinical management in viral drug resistance. We welcome original articles and reviews on the epidemiology of viral infections, the molecular mechanisms driving antiviral resistance, and advances in diagnostic tools for the early detection of resistant strains. By bringing together diverse perspectives from public health experts, virologists, epidemiologists, and clinicians, this Special Issue will promote interdisciplinary collaboration and innovative approaches to supporting the WHO Global Action Plan on Antimicrobial Resistance, to strengthen efforts to prevent and treat viral infections.

Topics of interest

• New strategies for preventing transmission: innovative approaches to the curbing of ongoing viral transmission through targeted prevention methods.
• Identifying undiagnosed infections: addressing infection unawareness and exploring novel rapid testing techniques to improve early detection.
• The surveillance of viral resistance: monitoring patterns of viral resistance to inform public health strategies and treatment protocols.
• Examining the socioeconomic determinants of viral resistance and their broader health and economic impacts.
• Implications of antiviral therapy: highlighting the need for appropriate and effective antiviral treatments and improving access to these therapies for affected populations.
• Raising awareness and promoting best practices: enhancing the understanding of viral resistance and best practices in prevention, diagnosis, and management across healthcare settings.

Prof. Dr. Nuno Taveira
Dr. Claudia Palladino
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Viruses is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.