Special Issue "Long-Term Outcomes of Treated Perinatal HIV Infection"

A special issue of Viruses (ISSN 1999-4915). This special issue belongs to the section "Animal Viruses".

Deadline for manuscript submissions: closed (31 August 2021).

Special Issue Editor

Dr. Dasja Pajkrt
E-Mail Website
Guest Editor
Department of Pediatric Infectious Diseases, Amsterdam University Medical Centers (Amsterdam UMC), location Academic Medical Center (AMC), 1105AZ Amsterdam, The Netherlands
Interests: pediatric viral infections; organoid technology

Special Issue Information

Dear Colleagues,

As a result of the successful implementation of potent combination antiretroviral therapy (cART), the life expectancy of perinatally HIV (PHIV)-infected children has been radically improved. Today, PHIV children with access to cART survive into adulthood. The long-term outcomes of growing up with HIV and lifelong exposure to cART treatment have, consequently, become an increasingly important topic, but PHIV has been highly understudied.

Lifelong exposure to HIV and the related antiviral treatment coincides with an important period in child development, for example, in the context of neurological and cognitive development. In this Special Issue, we will review outcomes for brain development, from a structural as well as a cognitive perspective.

Another long-term perspective that we will discuss in this Special Issue is the risk of cardiovascular diseases in PHIV children. In adults living with HIV, there is an increased risk of developing cardiovascular diseases as a consequence of atherosclerosis potentially due to chronic low-grade inflammation. To date, several studies have made similar observations in PHIV children. We will elaborate on the chronic low-grade systemic inflammation frequently found in PHIV children as one of the potential mechanisms underlying central nervous system abnormalities and atherosclerosis in PHIV children. 

Dr. Dasja Pajkrt
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Viruses is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • perinatally HIV-infected children
  • long-term outcomes
  • neurological abnormalities
  • neurocognitive development
  • cardiovascular risk

Published Papers

There is no accepted submissions to this special issue at this moment.
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