Immune Biomarkers in Veterinary Research: Challenges and Promises
A special issue of Veterinary Sciences (ISSN 2306-7381). This special issue belongs to the section "Veterinary Microbiology, Parasitology and Immunology".
Deadline for manuscript submissions: closed (30 June 2022) | Viewed by 8489
Special Issue Editors
Interests: immunology; veterinary infectious diseases; microbiology; innate immunity
Special Issues, Collections and Topics in MDPI journals
Interests: immunology; microbiology; innate immunity
Special Issue Information
Dear Colleagues,
The term biological marker appeared for the first time in literature in the late 1960s, but its definition and more common use started by the 1990s, when biomarkers were defined as “a characteristic that can be consistently and objectively measured and evaluated as an indicator of normal biological processes, pathogenic processes, or pharmacologic responses to a therapeutic intervention”, and they may consist of nucleic acids, proteins, metabolites, and even images.
Biomarkers have since been extensively used in veterinary medicine to evaluate health status, risk, diagnosis, prognosis, and progression of disease, to predict and monitor response to therapy, and to measure organs toxicity or failure. Immune biomarkers may have a special role in the biomarkers discovery because immune system interacts with all other systems, making the finding of new immune biomarkers relevant in disease progression and prognosis for many diseases.
The great expansion of new available technologies (e.g., DNA and RNA microarrays, protein microarrays, next generation sequencing, and mass spectrometry) give us an almost immediate access to big data repositories (e.g., genes, proteins, and metabolites expression), and a more comprehensive insight into the mechanisms of disease, as well as diagnostic and prognostic applications. For these reasons, the number and type of recognized immune biomarkers described in the literature and available for both clinical and nonclinical use have increased remarkably; however, in this area, only the tip of the iceberg has yet been discovered, and a lot is still unknown.
We invite authors to submit original research papers that address specific developments in immune biomarkers in infectious disease and vaccines, cancer, immunodeficiency, allergy and asthma, autoimmunity, and others. Topics may include but are not limited to immune biomarkers (cellular, molecular, or biochemical) used to evaluate normal biological processes, abnormal processes, biological responses, and likely outcomes of such processes in companion, farm, laboratory, and wildlife animal species.
Emphasis is put on correlates of protection induced by veterinary vaccines, immunomodulators and biological response modifiers altogether. Studies liaising the possible use of such markers to the current 3Rs policies (replacement, reduction, refinement) in the field of animal experiments are also encouraged.
Biomarkers of exposure to environmental, non-infectious stressors are also within the aforementioned scope of the Special Issue, in the framework of major issues of animal health and welfare.
Dr. Joel Fernando Soares Filipe
Dr. Federica Riva
Dr. Massimo Amadori
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Veterinary Sciences is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2100 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- immune biomarkers
- immunology
- animal health and welfare
- immune response
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