Bacterial Infectious Diseases in Animals: Epidemiology, Pathogenesis, and Control Strategies

A special issue of Veterinary Sciences (ISSN 2306-7381). This special issue belongs to the section "Veterinary Microbiology, Parasitology and Immunology".

Deadline for manuscript submissions: 30 June 2026 | Viewed by 695

Special Issue Editor


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Guest Editor
College of Animal Science and Technology, Henan University of Science and Technology, Luoyang 471000, China
Interests: veterinary; bacteria; infection; immunity; prevention

Special Issue Information

Dear Colleagues,

This Special Issue of Veterinary Sciences, titled “Bacterial Infectious Diseases in Animals: Epidemiology, Pathogenesis, and Control Strategies” is dedicated to advancing our understanding and management of bacterial pathogens that critically impact animal health, welfare, and productivity worldwide. In the face of evolving challenges such as antimicrobial resistance (AMR), intensification of animal production, and the interconnectedness of ecosystem health, there is an urgent need to consolidate contemporary research and foster innovative solutions. This collection aims to serve as a comprehensive resource by integrating multidisciplinary insights into the complex dynamics of bacterial diseases across various animal species.

The overall focus of this Special Issue is threefold: (a) to elucidate the epidemiological patterns of both established and emerging bacterial infections, including their transmission dynamics, host range, and environmental reservoirs; (b) to deepen the understanding of molecular and cellular pathogenesis, exploring virulence mechanisms, host-pathogen interactions, and immune evasion strategies; and (c) to evaluate and promote novel prevention and control strategies, encompassing vaccine development, diagnostic advancements, antimicrobial alternatives (e.g., probiotics, bacteriophages, immunomodulators), and sustainable management practices within a One Health framework.

Its scope encompasses original research articles, systematic reviews, and concise communications that present novel findings or synthesize current knowledge on bacterial pathogens affecting livestock, poultry, companion animals, and wildlife. We encourage submissions that employ advanced methodologies, from genomic surveillance and functional genomics to epidemiological modeling and controlled intervention studies. The core purpose is to bridge fundamental research with practical applications, facilitating the translation of scientific discoveries into effective tools and policies that enhance biosecurity, reduce economic losses, and mitigate public health risks associated with zoonotic pathogens.

This issue will usefully supplement the existing literature by providing a timely and synthesized platform that addresses critical gaps. While significant research exists on individual pathogens or specific control tools, there is a need for integrated analyses that connect epidemiological trends with pathogenesis insights to inform smarter interventions. Furthermore, this collection will specifically highlight strategies combating AMR—a priority area often treated in isolation—within the broader context of holistic disease management. By curating works that emphasize interdisciplinary approaches and the One Health paradigm, this Special Issue will offer a cohesive reference point that advances the field beyond fragmented knowledge, supporting the development of robust, adaptable, and sustainable control programs for the veterinary community and allied stakeholders.

Prof. Dr. Zhanqin Zhao
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Veterinary Sciences is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2100 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • veterinary
  • bacteria
  • epidemiology
  • pathogenesis
  • immunity
  • prevention
  • One Health

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Published Papers (1 paper)

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Research

18 pages, 3953 KB  
Article
Population Genetic Architecture of the Streptococcus suis Antigen HP0197
by Guopeng Mei, Junfeng Zhang, Lijun Guan, Shangbo Ning, Yun Xue and Zhanqin Zhao
Vet. Sci. 2026, 13(4), 376; https://doi.org/10.3390/vetsci13040376 - 13 Apr 2026
Viewed by 394
Abstract
S. suis is a major zoonotic infectious disease whose serological diversity brings challenges to vaccine development. Based on the whole-genome data of 169 S. suis strains, this study conducted a systematic bioinformatics analysis of the surface antigen protein HP0197 that reveals its distribution [...] Read more.
S. suis is a major zoonotic infectious disease whose serological diversity brings challenges to vaccine development. Based on the whole-genome data of 169 S. suis strains, this study conducted a systematic bioinformatics analysis of the surface antigen protein HP0197 that reveals its distribution characteristics, sequence diversity, domain composition and antigenic epitope distribution. The results showed that the HP0197 gene, which has a detection rate of 91.72%, can be divided into seven major phylogroups (I–VII) and the following two structural types: short form (HP0197-S) and long form (HP0197-L). All sequences contained signal peptides, transmembrane structures, LPXTG anchoring motifs, as well as conserved GAGBD and G5 domains, among which tandem repeats of the G5 domain existed in the long HP0197-L type. Tertiary structure prediction indicated that HP0197 has a spatial architecture of “conserved at both ends and flexible in the middle”, in which B-cell epitopes are mainly enriched near the GAGBD and G5 domains, suggesting these regions are the key targets for inducing cross-immune protection. It systematically elucidates the diversity and structural characteristics of the HP0197 protein from the perspective of population genetics, which provides a theoretical basis for optimizing existing subunit vaccines, designing broad-spectrum multi-epitope vaccines and exploring novel anti-infection strategies. Full article
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