Spider Venoms
A special issue of Toxins (ISSN 2072-6651).
Deadline for manuscript submissions: closed (31 October 2010) | Viewed by 32766
Special Issue Editors
Interests: spider venom chemical diversity; mechanisms of venom evolution; phylogenetic patterns of venom diversity
Special Issue Information
Dear Colleagues,
Spider venoms are a treasure trove of chemical and pharmacological diversity. Over 41,000 described species of spiders have evolved from a common ancestor that lived at least 350 million years ago. Since that time, spider venoms have been evolving as predatory tools in the context of diversifying tactics of prey capture. The end products are thus extraordinarily refined cocktails comprising hundreds of toxins endowed with exquisite selectivity and affinity. As the size of these vast biochemical stores may be up to forty million components, they represent a truly phenomenal potential for discovery. Yet venoms of only a few scattered twigs on the spider family tree have been analyzed and less than 1500 toxins described. Even fewer have been well characterized but nevertheless show immense promise as drug leads for pathologies ranging from pain to erectile dysfunction. Modern methods for proteome and transcriptome analyses are exponentially increasing the pace of discovery. As we begin to explore divergent spider lineages we are improving understanding of patterns of toxin diversity and the evolutionary processes that have generated it, which will help guide exploration for novel pharmacology. For this special issue we invite contributions from spider venom researchers with foci on a broad range of spider toxin issues, and from an equally broad range of research approaches.
Prof. Dr. Greta J. Binford
Dr. Pierre Escoubas
Guest Editors
Keywords
- Araneae
- venom
- phylogeny
- peptides
- proteins
- bioactivity
- pharmacology
- drug development
- neurotoxin
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.
Further information on MDPI's Special Issue policies can be found here.
