Special Issue "Biological Toxins: Challenges and Medical Countermeasures"
A special issue of Toxins (ISSN 2072-6651).
Deadline for manuscript submissions: closed (31 October 2021) | Viewed by 1917
Since recent bioterrorists incidents worldwide, dealing with a wide range of biological toxins is now recognized as vital for an effective response to a bioterrorist attack. Adequate preparedness is of utmost importance in a world increasingly dominated by several bioterrorist threat. Raising awareness of international institutions, national governments and other public and private funding sources to the benefits of countermeasures and the need to stockpile them in advance is also paramount. The immense diversity of microorganisms, animals, insects and plants producing toxins, and toxins subtypes, represent a major challenge. As a consequence, there is a pressing need for the development of potential effective countermeasures against biological weapons. Moreover, botulinum toxin is also available in licensed drugs for the treatment of a variety of medical disorders, in addition to increased use in cosmetic and aesthetic medicine. A wide range of available in vitro analytical tools are currently employed globally for countermeasures assessments. However there is also a need to reduce animal use globally. The evaluation of currently available in vitro methods for replacement of animal tests able to entirely replace animal model will have a great impact on public health and economy.
Dr. Christine Rasetti-Escargueil
Manuscript Submission Information
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- botulinum neurotoxins
- staphylococcal enterotoxins
- replacement tests