Special Issue "Clinical and Molecular Analytic in Neuro-Oncology"
Deadline for manuscript submissions: 30 June 2022.
Interests: gliobastoma; intrinsic brain tumors; spinal intramedullary tumors
Interests: spinal intramedullary tumors; primary brain tumors
Interests: glioblastoma; primary brain tumors; low-grade gliomas; spinal intramedullary tumors
Interests: gliobastoma; intrinsic brain tumors; spinal intramedullary tumors; eloquent area neurosurgery
Special Issues and Collections in MDPI journals
In the last years, great steps beyond in the understanding of the molecular pathophysiology of both primary and metastatic brain tumors have been made, thus producing a notable improvement of their clinical management. The role of the 1p/19q translocation along with the IDH mutation status have been unanimously recognized and acknowledged as key factor for defining the biological behavior of the lesions, as well as MGMT methylation status has been extensively investigated as predictor of the treatment response in the primary brain neoplasms. Such specific molecular patterns have been even associated to precise radiological appearances and clinical phenotypes, such as for instance in the more extensive expected neuropsychological impairment in patients suffering from IDH wild type Diffuse Astrocytomas in respect to their mutated counterparts. In Brain Metastases (BM) research, a wave of molecular findings has renewed our old conception of the “metastatic phenotype”, transforming it in a more wide and complex network of interactions between cytokines, microenvironment and adhesions molecules. The advanced Neuroimaging research is currently providing an increasing amount of evidences concerning the radiological implications of the molecular phenotypes of the lesions; this is not only particularly significant for PBTs and BMs, but for intracranial meningiomas and lymphomas either.
Therefore, with pleasure, we invite investigators to contribute to this Special Issue with original research articles, review articles and meta-analysis articles focusing on the current knowledge of the molecular pathogenesis of the Brain Tumors, with special regard to their clinical, radiological and surgical implications for the Neuro-oncologic practice.
Dr. Alessandro Pesce
Prof. Dr. Angelo Pompucci
Prof. Dr. Maurizio Salvati
Prof. Dr. Alessandro Frati
Manuscript Submission Information
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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- Primary Brain Tumors
- Low-grade gliomas
- Spinal intramedullary tumors
- Brain metastases
- MRI Spectroscopy
- Molecular analytic in Neuro-oncology
- Advanced Neuroimaging in Neuro-oncology