Special Issue "Biological Relationship between Skeletal Muscle and Whole-Body Health"

A special issue of Sports (ISSN 2075-4663).

Deadline for manuscript submissions: 31 May 2019

Special Issue Editor

Guest Editor
Dr. Robert A. Jacobs

Human Physiology & Nutrition Program, Department of Biology, University of Colorado Colorado Springs, CO, USA
Website 1 | Website 2 | E-Mail
Interests: mitochondria; aging; insulin resistance; redox; human performance; bioenergetics; hypoxia

Special Issue Information

Dear Colleagues,

Skeletal muscle accounts for ~40% of total body mass and ~75% of variability in the basal metabolic rate, which is, on average, the largest component of total daily energy expenditure, and is the only tissue in the human body capable of increasing metabolic demand >1,000-fold in response to extreme metabolic stress. Whole-body health tracks with skeletal muscle function, and skeletal muscle health is reliant on the maintenance of mitochondrial function. Diminished skeletal muscle and mitochondrial function is now evident in the etiology and/or pathology of many diseases and disorders, especially metabolic disease. Moreover, biological decrements concomitant to aging are complementary to diminished skeletal muscle and mitochondrial function. The direction that these relationships take is largely attributed to the regularity and magnitude of energetic flux through skeletal muscle. Exercise is a necessary strategy to stimulate and/or maintain skeletal muscle and mitochondrial function across the lifespan. Accordingly, it is paramount to identify the physiology of skeletal muscle and mitochondrial function vs. dysfunction, and discuss how energetic flux relates to both. Therefore, the aim of this Special Issue is to discuss the biological relationship between skeletal muscle as well as mitochondrial function in relation to whole-body health.

Dr. Robert A. Jacobs
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Sports is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 350 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • mitochondria
  • aging
  • insulin resistance
  • redox
  • contraction
  • exercise

Published Papers

This special issue is now open for submission.
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