Application of Chromatography in Bioactive Compound Analysis
A special issue of Separations (ISSN 2297-8739). This special issue belongs to the section "Analysis of Natural Products and Pharmaceuticals".
Deadline for manuscript submissions: 10 February 2026 | Viewed by 28
Special Issue Editors
Interests: phytochemistry; chromatography; sample preparation; extraction
Special Issues, Collections and Topics in MDPI journals
Interests: phytochemicals; antioxidant activity; extraction
Special Issue Information
Dear Colleagues,
Chromatography plays a key role in modern analytical chemistry, especially in the study of bioactive compounds from complex natural and synthetic samples. This Special Issue focuses on the wide application of chromatography—not only for the detection and quantification of compounds but also in sample preparation, including extraction steps. Techniques such as HPLC, GC, and LC-MS, combined with modern detectors, continue to provide fast, reliable, and validated results in fields such as food analysis, pharmaceuticals, and biomedical research.
We welcome original research and review articles that focus on the analysis of bioactive compounds using new or improved chromatographic methods. Particular attention will be given to studies that emphasize the role of bioactive molecules in promoting health, as well as their occurrence in food, medicinal plants, and pharmaceutical products. We especially encourage submissions that combine effective extraction methods with reliable chromatographic techniques—such as LC-MS or GC-MS—to achieve accurate and comprehensive analysis of bioactive compounds.
Studies involving statistical analysis, method validation, or optimization of analytical parameters are also highly encouraged.
We look forward to your contributions to this Special Issue.
Prof. Dr. Milan N. Mitić
Prof. Dr. Vesna Stankov-Jovanovic
Dr. Jelena S. Nikolić
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Separations is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- analytical method validation
- sample preparation
- antioxidant compounds
- phytochemicals
- chromatography
- bioactive compounds
- natural products
- LC-MS
- HPLC
- GC-MS
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.
Further information on MDPI's Special Issue policies can be found here.
