Special Issue "Single Biomolecule Detection"


A special issue of Sensors (ISSN 1424-8220). This special issue belongs to the section "Biosensors".

Deadline for manuscript submissions: 15 August 2014

Special Issue Editor

Guest Editor
Prof. Dr. Masateru Taniguchi
The Institute of Scientific and Industrial Research, Osaka University, 8-1 Mihogaoka, Ibaraki, Osaka 567-0047, Japan
Website: http://www.bionano.sanken.osaka-u.ac.jp/
E-Mail: taniguti@sanken.osaka-u.ac.jp
Phone: +81-6-6879-8445
Fax: +81-6-6875-2440
Interests: single molecular science; single molecular devices; nanofabrications

Special Issue Information

Dear Colleagues,

Single-biomolecule detection technologies with high throughput and high accuracy can provide new information in the fields of medical science and biology, and they are expected to be utilized as innovative technologies in the future development of medical treatments and drugs. An ideal single-biomolecule detection technology can identify targeted biomolecules and analyze blood and spittle containing specific biomolecules using an integrated chip, where pretreatment devices exclude all molecules except targeted molecules and after-treatment devices identify and treat targeted molecules. For example, using an integrated chip composed of MEMS/NEMS and nanopores, DNA molecules are separated/extracted from blood and sequenced by MEMS/NEMS and nanopore devices, respectively. However, pretreatment and after-treatment devices are developed individually in different fields, and there are few integrated devices that facilitate both pretreatment and after-treatment processes. Integration is a big barrier for practical single-biomolecule detection technologies.

The aim of this special issue is to furnish an opportunity to break through the barrier and discover innovative single-biomolecule detection technologies. Therefore, the papers include a wide range of studies regarding pretreatment, after-treatment, and integration devices, including MEMS, NEMS, fluid devices, nanopore devices, and single-molecule optical and electrical detection technologies.

Both review articles and original research papers relating to pretreatment and after-treatment devices are solicited. There is particular interest in papers concerning technologies where optical, electrical, and magnetic detections are performed using pretreatment and after-treatment devices fabricated by microfabrication technologies in order to focus on practical applications of single-biomolecule detection technologies using integrated devices.

Prof. Dr. Masateru Taniguchi
Guest Editor

Related Special Issues
Molecular Devices and Machines: Cooperativity and Multifunctionality


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  • Single biomolecules
  • Nanopore
  • Pretreatment devices
  • After-treatment devices

Published Papers (4 papers)

Sensors 2014, 14(4), 6056-6083; doi:10.3390/s140406056
Received: 20 December 2013; in revised form: 10 March 2014 / Accepted: 21 March 2014 / Published: 27 March 2014
Show/Hide Abstract | Download PDF Full-text (1056 KB) |  Supplementary Files
abstract graphic

Sensors 2014, 14(3), 5174-5182; doi:10.3390/s140305174
Received: 9 December 2013; in revised form: 25 February 2014 / Accepted: 7 March 2014 / Published: 12 March 2014
Show/Hide Abstract | Download PDF Full-text (383 KB)

Sensors 2014, 14(2), 2449-2467; doi:10.3390/s140202449
Received: 14 December 2013; in revised form: 22 January 2014 / Accepted: 27 January 2014 / Published: 3 February 2014
Show/Hide Abstract | Download PDF Full-text (2667 KB) | Download XML Full-text

Sensors 2014, 14(1), 1195-1207; doi:10.3390/s140101195
Received: 18 December 2013; in revised form: 3 January 2014 / Accepted: 7 January 2014 / Published: 10 January 2014
Show/Hide Abstract | Download PDF Full-text (370 KB) | View HTML Full-text | Download XML Full-text

Last update: 27 February 2014

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