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Colorimetric Sensors: Methods and Applications (2nd Edition)

A special issue of Sensors (ISSN 1424-8220). This special issue belongs to the section "Chemical Sensors".

Deadline for manuscript submissions: 30 June 2025 | Viewed by 1021

Special Issue Editors


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Guest Editor
School of Chemistry and Chemical Engineering, Chongqing University, Chongqing 401331, China
Interests: chromatographic analysis; spectroscopic analysis; enzyme immobilizations and applications; preparation and applications of materials with enzyme-like activity
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
Nanyang Environment and Water Research Institute, Nanyang Technological University, Singapore 637141, Singapore
Interests: analytical and bioanalytical chemistry
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Colorimetric sensors have attracted considerable attention for many sensing applications due to the potential for rapid analysis, cost effectiveness, ease of use, simple detection systems, or even naked-eye observations. Currently, a number of colorimetric sensors have been developed for the sensing of small molecules, including cations, anions, and neutral species and essential cellular components related to human living systems in solutions and biological samples, as well as therapeutic and diagnostic applications. In this Special Issue, we will take particular interest in manuscripts that discuss the principles and mechanisms, fabrication methods, and relevant applications in various fields of colorimetric sensors. We invite authors to contribute original research and review articles that will stimulate more basic research on the development of colorimetric sensors.

Potential topics suitable for this Special Issue include, but are not limited to, the following: colorimetric sensing principles and mechanisms; nanomaterials for colorimetric (bio)sensors for biomedical applications; paper-based colorimetric sensors; colorimetric sensors toward cations, anions, and biomolecules; and colorimetric strips.

Prof. Dr. Fengqing Yang
Dr. Liya Ge
Guest Editors

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Keywords

  • colorimetric sensors
  • paper-based colorimetric sensors
  • chemical sensors
  • biosensors
  • colorimetric strips
  • colorimetric sensing arrays

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Published Papers (1 paper)

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Research

18 pages, 3506 KiB  
Article
Colorimetric 3D microPAD for Multiplexed Detection of Paracetamol and Aspirin in Urine and Saliva
by Alberto Abalde-Pujales, Vanesa Romero, Isela Lavilla and Carlos Bendicho
Sensors 2025, 25(6), 1756; https://doi.org/10.3390/s25061756 - 12 Mar 2025
Viewed by 477
Abstract
In this work, a novel 3D μPAD cellulose-based colorimetric chemosensor for multiplexed detection of paracetamol and aspirin in biological samples is proposed. The easy availability of analgesics such as paracetamol and non-steroidal anti-inflammatory drugs such as aspirin, over-the-counter drugs that can be acquired [...] Read more.
In this work, a novel 3D μPAD cellulose-based colorimetric chemosensor for multiplexed detection of paracetamol and aspirin in biological samples is proposed. The easy availability of analgesics such as paracetamol and non-steroidal anti-inflammatory drugs such as aspirin, over-the-counter drugs that can be acquired without medical prescription, can entail a health problem if they are administered incorrectly. The development of analytical procedures for the rapid, sensitive, and accurate determination of such drugs in clinical samples is of utmost importance. Different parameters involved in the design of the 3D μPAD system and the colorimetric reaction conditions have been optimized. Under optimal conditions, detection limits of 0.004 mM and 0.013 mM were obtained for paracetamol and aspirin, respectively. The proposed procedure was validated against two certified reference materials and applied to the analysis of several synthetic urine and saliva samples. Synthetic urine and saliva samples were spiked at two concentration levels, showing recoveries in the range of 98–103% with a relative standard deviation of 3–6% (n = 6). Full article
(This article belongs to the Special Issue Colorimetric Sensors: Methods and Applications (2nd Edition))
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