Anticancer Potential of Natural Products

Special Issue Editor


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Guest Editor
Division of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, The Ohio State University, Columbus, OH 43210, USA
Interests: natural product anticancer drug design and discovery; isolation of the bioactive components from natural resources supported by chromatography techniques; determination of the complete structures of the isolates by analysis of their spectroscopic and the single-crystal X-ray diffraction data; synthetic modification of the lead compounds determined through organic reactions; evaluation of bioactivities of the isolates, using specific bioassays; characterization of mechanisms of action of the bioactive compounds through various bioassays; identification of the molecular targets for the lead compounds through a series of bioassays supported with molecular modeling

Special Issue Information

Dear Colleagues,

Cancer becomes one of the most serious diseases, and major of the cutrrent cancer chemotherapy is insufficient for complete treatment of cancer, due to the adverse effects and the development of multidrug resistance. Natural products mediate their bioactivities through different cellular mechanisms, of which several compounds have been developed succssfully as anticancer agents. In addition, many of these products have been reported for their immunoregulatory property, which is supportive of cancer immunotherapy, one of the most promisin therapies for the treatment of cancer. Thus, further investigations on natural products could provide critical information for the development of effective anticancer agents. This special issue aims to investigate a journey of the development of natural products as effective anticancer agents. We thus welcome Original Research, Review, Mini Review, and Perspective articles on this theme, including but not limited to:

  • Identification of natural products showing potential anticancer activity.
  • Structural insights and medicinal chemistry for synthetic modifications on natural products.
  • Oncology biology for testing potential anticancer activity of natural products.
  • Molecular biology and modeling for identification of the molecular targets of natural products.
  • Tumor immunity about natural products.

Dr. Yulin Ren
Guest Editor

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Keywords

  • anticancer agents
  • anticancer drug design and discovery
  • molecular modeling
  • molecular targets
  • natural products
  • synthetic modification
  • tumor immunity

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Published Papers

This special issue is now open for submission.
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