Mass Spectrometry-Based Quantitative Proteomics

Dear Colleagues, 

Organisms adapt their cellular activities to internal and external environments by regulating gene and protein expression as well as a series of protein post-translational modifications and protein–protein interactions. In recent years, proteomics has emerged as the key technology to understand how proteins work together in a coordinated fashion to execute biological functions. In addition, remarkable technological advances have been achieved due to improvements in proteomic sample preparation and mass spectrometry analysis, which allow refining the coverage of total proteomes and sub-proteomes from small amounts of starting material and characterizing post-translational modifications and protein–protein interactions. Furthermore, quantitative spatial and temporal proteomics now provides detailed information on organ- and tissue-specific regulatory mechanisms responding to a variety of individual stresses or stress combinations during the cell life cycle. Finally, the development of computational and bioinformatic tools allows managing the tremendous amount of data generated by mass spectrometers to deliver relevant biological information. Thus, powerful mass spectrometry-based proteomics technologies now provide unprecedented insights into the composition, structure, function, and control of the proteome, shedding light on complex biological processes and phenotypes. 

This Special Issue of Proteomes on “Mass Spectrometry-Based Quantitative Proteomics” welcomes submissions of original research or review articles aiming at deciphering mechanistic and quantitative physiological processes with the use of proteomics tools. Authors are welcome to submit contributions focusing on the dynamic changes of protein expression in their native and modified forms, analyzed by combining several “omics” approaches in contrasted physiological or stress situations as well as by applying technical advances in the proteomic field. Multidisciplinary articles dealing with model or non-model organisms in all areas of plant and animal biology, plant and animal health, as well as abiotic and biotic stress responses will be accepted for this Special Issue.  

Dr. Uma K. Aryal
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-anonymized peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Proteomes is an international peer-reviewed open access quarterly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.