Proteomic Analysis of Host-Microbial Pathogen Interactions

Dear Colleagues,

In the last decade, proteomic technologies and the associated computational analysis methods have advanced to a level that not only permits studies on the interrogation of host-pathogen interactions using model systems (e.g., cell co-cultures) but also clinical samples. I encourage contributions associated with various infectious diseases, the use of different technologies (e.g., mass spectrometry-based proteomics, protein arrays and antibody arrays), different pathogens (e.g., bacteria, fungi and protozoa), different hosts (human, animals and plants), co-infections with viral/bacterial pathogens and host-pathogen interactions in the context of a resident microbiome. Contributions may also focus on infectious disease diagnosis, the antimicrobial treatment and antibiotic resistance of a pathogen if the host environment is a component of the research. Furthermore, articles related to technical advances in proteomics that facilitate the study of host-pathogen interactions are welcome.

Proteomic research on host-pathogen interactions can drive the discovery of novel therapeutic targets for infectious diseases, discover new mechanisms of pathogenesis, unravel the complexity of an infectious disease and, in the context of mammalian hosts, characterize the immune response towards an invading pathogen. Proteomic research can provide critical insights into the communications of more than one microbial species, including those that do not harm the host, with the host environment. This is an exciting time to push this technology further into the limelight of host-pathogen interaction research and to demonstrate its important role in infectious disease systems biology.

We look forward to receiving your manuscripts.

Prof. Dr. Rembert Pieper
Dr. Yanbao Yu
Guest Editor

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