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Processes
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Polymeric Hydrogels for Biomedical Applications
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Polymeric Hydrogels for Biomedical Applications

A special issue of Processes (ISSN 2227-9717). This special issue belongs to the section "Materials Processes".

Deadline for manuscript submissions: closed (10 August 2021) | Viewed by 2609

Special Issue Editor

Dr. Yuki Akagi

E-Mail Website
Guest Editor
Graduate School of Engineering, The University of Tokyo, Tokyo 113-8654, Japan
Interests: biomaterials; polymer science; hydrogels; stimulus responsiveness; drug delivery system
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Hydrogels, due to their high water content and structure close to living organisms, are used as versatile biomedical materials in industries and research. Recently, research on functionalization of the polymers and frameworks of hydrogels, as well as separation and material transportation utilizing their network structure, has been highlighted.

The objective of this Special Issue is to deepen our knowledge on hydrogels aimed at biomedical application from a broader perspective. From the design and synthesis of the structure polymers to the proposition, development, and elucidation of processes involved in a variety of phenomena that appertain hydrogels, such as gelation, functionalization, drug release, and separation, we extend our scope with the aim to introduce new knowledge on hydrogel to accelerate its application as well as to seek unprecedented potentials of hydrogels as a biomedical material.

Dr. Yuki Akagi
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Processes is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Published Papers (1 paper)

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Review

18 pages, 2049 KiB  
Review
The Advantages of Polymeric Hydrogels in Calcineurin Inhibitor Delivery
by Claudia Sandoval-Yañez, Leslie Escobar and Cristián A. Amador
Processes 2020, 8(11), 1331; https://doi.org/10.3390/pr8111331 - 22 Oct 2020
Viewed by 2792
Abstract
In recent years, polymeric hydrogels (PolyHy) have been extensively explored for their applications in biomedicine as biosensors, in tissue engineering, diagnostic processes, and drug release. The physical and chemical properties of PolyHy indicate their potential use in regulating drug delivery. Calcineurin inhibitors, particularly [...] Read more.
In recent years, polymeric hydrogels (PolyHy) have been extensively explored for their applications in biomedicine as biosensors, in tissue engineering, diagnostic processes, and drug release. The physical and chemical properties of PolyHy indicate their potential use in regulating drug delivery. Calcineurin inhibitors, particularly cyclosporine (CsA) and tacrolimus (TAC), are two important immunosuppressor drugs prescribed upon solid organ transplants. Although these drugs have been used since the 1970s to significantly increase the survival of transplanted organs, there are concerns regarding their undesirable side effects, primarily due to their highly variable concentrations. In fact, calcineurin inhibitors lead to acute and chronic toxicities that primarily cause adverse effects such as hypertension and nephrotoxicity. It is suggested from the evidence that the encapsulation of calcineurin inhibitors into PolyHy based on polysaccharides, specifically alginate (Alg), offers effective drug delivery with a stable immunosuppressive response at the in vitro and in vivo levels. This not only may reduce the adverse effects but also would improve the adherence of the patients by the effective preservation of drug concentrations in the therapeutic ranges. Full article
(This article belongs to the Special Issue Polymeric Hydrogels for Biomedical Applications)
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