Animal Models for Diabetes
A special issue of Processes (ISSN 2227-9717). This special issue belongs to the section "Biological Processes and Systems".
Deadline for manuscript submissions: closed (31 May 2022) | Viewed by 7187
Special Issue Editor
Special Issue Information
Dear Colleagues,
In recent decades, substantial progress has been made in understanding diabetes and the molecular mechanisms of its diverse symptoms. The streptozotocin-induced diabetes model in rodents was a significant breakthrough in this field. Today, diabetes affects more than 9% of the world’s population, with the numbers only expected to increase over time. Diabetes complications remain one of the leading causes of visual impairment and disability. There is a high demand for new models of diabetes that recapitulate not only insulin deficiency but lifestyle-associated diabetes metabolism disorders and obesity-related glucose intolerance, which are major factors contributing to the incidence of diabetes. This Special Issue, "Animal Models for Diabetes", aims to assemble the most advanced knowledge on the new approaches to modeling diabetes and high-glucose conditions. This issue's scope is not limited to models in research animals, and submissions of in vitro, 3D culture, microfluidics, and tissue organoid models of diabetes and its aspects are equally encouraged. We welcome models that can provide insights into molecular events and signaling pathways and their role in diabetes-associated pathologies, as well as models that can lead to new translational discoveries and direct therapeutic approaches to the diverse complications of diabetes. These manuscripts may include research articles and reviews.
Dr. Anton Lennikov
Guest Editor
Manuscript Submission Information
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Keywords
- hyperglycemia
- high-fat diet
- energy metabolism
- blood-retinal barrier
- leukostasis
- glucose intolerance
- insulin resistance
- autoimmune diabetes
- diabetic nephropathy
- transgenic animals
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