Numerical Modeling and Simulation of Multiphase Flows in Industrial and Environmental Applications

Dear Colleagues,

Multiphase flows—such as gas–solid, liquid–gas, solid–liquid, and three-phase systems—play a fundamental role in various engineering, environmental, biological, and natural processes. They are critical to the optimum design and safe operation of systems in chemical processing, energy, pharmaceuticals, and food production industries. Moreover, multiphase phenomena also appear in natural and biological systems, where a deeper understanding is essential.

As engineering systems grow in size and are pushed to operate under more demanding conditions, an accurate understanding of the underlying physics governing multiphase flows becomes indispensable—not only for safety but also for ensuring economic efficiency. Traditionally, the design of such systems has relied on static experimental correlations. However, there is a growing shift toward using mathematical models capable of predicting dynamic behavior, such as transient responses and system stability. Although experimental studies remain valuable, they are often expensive and time-consuming. In contrast, advances in computational fluid dynamics (CFDs), numerical algorithms, and computational power now provide powerful tools for exploring the complex physics of multiphase flows across scales. Because realistic and accurate models of two-phase or multiphase flow are inherently complex and rarely solvable analytically, so they must be addressed through numerical methods implemented within CFD frameworks. These tools are essential for predicting operational limits, guiding optimal design, and ensuring safe control of modern multiphase systems.

This Special Issue, “Numerical Modeling and Simulation of Multiphase Flows in industrial and environmental applications”, invites original research and review articles showcasing recent progress in multiphase flow modeling, simulation, and analysis. We welcome contributions that address fundamental advances, practical applications, or methodological innovations in numerical modeling and simulation of multiphase flows, particularly those that enhance predictive capabilities or reduce computational costs.

Topics of interest include, but are not limited to:

• Development, verification, and validation of advanced CFD models (e.g., particle-resolved DNS, DEM/CGDEM, two-fluid models, MPPIC);
• Modeling and simulations of turbulent multiphase flow, both reactive and non-reactive;
• Heat and mass transfer in multiphase flows;
• Multiscale modeling and simulation strategies (micro, meso, macro);
• Applications of CFD to reactor design, optimization, and scale-up;
• Integration of machine learning with CFD models;
• High-performance computing (e.g., parallel computing, GPU acceleration, hybrid CPU–GPU frameworks).

We look forward to your valuable contributions that will advance the understanding and application of numerical tools in multiphase flow systems.

Prof. Dr. Santiago Lain
Dr. Aldo Benavides-Moran
Dr. Juan Ricardo Vidal Medina
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Processes is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• computational fluid dynamics
• machine learning
• particles, bubbles, and droplets
• multiscale modeling
• heat and mass transfer
• reactive and non-reactive multiphase flows
• turbulence