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Processes
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Supercritical Fluid Technology and Its Applications in Separation Processes
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Supercritical Fluid Technology and Its Applications in Separation Processes

A special issue of Processes (ISSN 2227-9717). This special issue belongs to the section "Separation Processes".

Deadline for manuscript submissions: 25 July 2025 | Viewed by 649

Special Issue Editors

Dr. Leandro Ferreira Pinto

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Guest Editor
Departamento de Engenharia, Faculdade de Engenharia e Ciências, Universidade Estadual Paulista (UNESP), Rosana 19274-000, SP, Brasil
Interests: supercritical technology; supercritical water; supercritical extraction; thermodynamics; fluid phase equilibria; high pressures
Prof. Dr. Lúcio Cardozo Filho

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Guest Editor
Departamento de Engenharia Química, Faculdade de Engenharia e Ciências, Universidade Estadual de Maringá (UEM), Maringá 87020-900, PR, Brasil
Interests: supercritical technology; supercritical water; supercritical extraction; thermodynamics; fluid phase equilibria; high pressures
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

This Special Issue of Processes is dedicated to exploring the advancements and applications of supercritical fluid technology, an area that continues to revolutionize separation and transformation processes in industry. Supercritical fluids offer innovative and sustainable solutions to various industrial challenges, owing to their unique properties, which combine the characteristics of liquids and gases.

The scope of this Special Issue covers topics such as the extraction of natural products using supercritical fluids, which are noted for their efficiency and environmental friendliness. We also explored the application of supercritical water in gasification and oxidation processes, offering new perspectives for waste treatment and clean energy generation.

Another focus is the study of the phase equilibrium in pressurized systems with supercritical fluids, which is essential for developing more efficient processes. This Special Issue also addresses innovations in supercritical fluid chromatography, an emerging analytical technique recognized for its high efficiency and selectivity.

By combining cutting-edge research and case studies, this Special Issue aims to provide a comprehensive and updated view of the potential of supercritical fluids, serving as a valuable resource for researchers and industry professionals interested in exploring and applying this innovative technology.

Dr. Leandro Ferreira Pinto
Prof. Dr. Lúcio Cardozo Filho
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Processes is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • supercritical fluids
  • extraction
  • gasification
  • phase equilibrium
  • chromatography
  • sustainability

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Published Papers (1 paper)

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Research

11 pages, 2174 KiB  
Article
Proof-of-Concept Study on Supercritical Fluid Chromatography Hyphenated with a Fast Optoelectronic Nose for Online Monitoring of Odorant Molecules
by Cyrille Santerre, David Touboul, Thierry Livache and Cyril Herrier
Processes 2025, 13(5), 1425; https://doi.org/10.3390/pr13051425 - 7 May 2025
Viewed by 438
Abstract
In this study, we explored the use of surface plasmon resonance (SPR) and Mach–Zehnder interferometry for detecting compounds in complex mixtures separated by supercritical fluid chromatography. Each molecule was individually injected and analyzed by supercritical fluid chromatography (SFC) in a 10% alcoholic solution. [...] Read more.
In this study, we explored the use of surface plasmon resonance (SPR) and Mach–Zehnder interferometry for detecting compounds in complex mixtures separated by supercritical fluid chromatography. Each molecule was individually injected and analyzed by supercritical fluid chromatography (SFC) in a 10% alcoholic solution. The fingerprints obtained via the sensors were then compared to the fingerprints of the same molecules present in a lemon essential oil (EO) at the same dilution. The results show a remarkable correlation between UV sensors and electronic noses (e-nose), enabling compound detection. The obtained signals are normalized and presented as radar charts to visualize the specific olfactory signatures of each molecule. The olfactory profiles of monoterpenes C10H16 such as α-pinene and limonene show notable differences, as do the C10H16O isomers (citral, geranial, and neral). Mach–Zehnder interferometry also allows for the discrimination of limonene enantiomers, a challenging task for current chromatography techniques. Statistical analysis confirms the ability of these technologies to differentiate compounds, including isomers. Even if UV detection is more sensitive than SPR, e-noses (SPR and Mach–Zehnder interferometers) offer the unique advantage of providing specific signatures for each compound, facilitating real-time identification. This study demonstrates the effectiveness of combining e-noses with SFC for rapid, non-destructive detection of volatile compounds. This concept can be extended to other terpenoids and volatile compounds, and hybridization with gas chromatography could be a future potential development. Full article
(This article belongs to the Special Issue Supercritical Fluid Technology and Its Applications in Separation Processes)
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