Antimicrobial Gels

A special issue of Polymers (ISSN 2073-4360). This special issue belongs to the section "Polymer Applications".

Deadline for manuscript submissions: closed (20 September 2021) | Viewed by 7772

Special Issue Editor


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Guest Editor
Biomimetic Materials and Tissue Engineering Laboratory, Department of Chemical Engineering, University of South Carolina, Columbia, SC 29208, USA
Interests: bioinspired gels; gels for stem cell delivery; self-assembled micelles for growth factor immobilization; models gels to control cell microenvironment; composite materials with structure at multiple length scales; skeletal tissue engineering
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Special Issue Information

Dear Colleagues,

The SARS-CoV-2 pandemic has brought the fight against the spread of harmful microbes, especially viruses, to the forefront of research. The discovery and development of novel antimicrobial soft materials (particularly gels) as surface coatings is crucial to our effort to stop the spread of viral agents. Further, there is a need to understand the mechanism of microbial interaction and the molecular basis of antimicrobial and antiviral properties of gels and other soft materials. Gels and other soft materials are used in many different forms as thin films; porous, non-porous, and fibrous coatings; micro- and nanoparticles; viscous gels; and solutions to deactivate and neutralize antimicrobial and antiviral agents. Related topics in this Special Issue include the molecular basis of the antimicrobial activity of soft materials, the mechanism of interaction of microbial agents with soft materials and gels, characterization of the antimicrobial activity of soft materials and gels, and the adhesion of microbial agents—particularly viruses—to gels and other soft materials. Other topics include the synthesis, characterization, and processing of novel antimicrobial and antiviral gels; synthetic and natural, hybrid, and composite antimicrobial gels; and gels for the long-term, sustained, and controlled release of antimicrobial agents. 

Prof. Dr. Esmaiel Jabbari
Guest Editor

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Keywords

  • antimicrobial
  • antiviral
  • gels
  • hydrogels
  • soft materials
  • adhesion
  • antimicrobial activity

Published Papers (1 paper)

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Research

12 pages, 7348 KiB  
Article
Protective Face Mask Filter Capable of Inactivating SARS-CoV-2, and Methicillin-Resistant Staphylococcus aureus and Staphylococcus epidermidis
by Miguel Martí, Alberto Tuñón-Molina, Finn Lillelund Aachmann, Yukiko Muramoto, Takeshi Noda, Kazuo Takayama and Ángel Serrano-Aroca
Polymers 2021, 13(2), 207; https://doi.org/10.3390/polym13020207 - 8 Jan 2021
Cited by 55 | Viewed by 7030
Abstract
Face masks have globally been accepted to be an effective protective tool to prevent bacterial and viral transmission, especially against indoor aerosol transmission. However, commercial face masks contain filters that are made of materials that are not capable of inactivating either SARS-CoV-2 or [...] Read more.
Face masks have globally been accepted to be an effective protective tool to prevent bacterial and viral transmission, especially against indoor aerosol transmission. However, commercial face masks contain filters that are made of materials that are not capable of inactivating either SARS-CoV-2 or multidrug-resistant bacteria. Therefore, symptomatic and asymptomatic individuals can infect other people even if they wear them because some viable viral or bacterial loads can escape from the masks. Furthermore, viral or bacterial contact transmission can occur after touching the mask, which constitutes an increasing source of contaminated biological waste. Additionally, bacterial pathogens contribute to the SARS-CoV-2-mediated pneumonia disease complex, and their resistance to antibiotics in pneumonia treatment is increasing at an alarming rate. In this regard, herein, we report the development of a non-woven face mask filter fabricated with a biofunctional coating of benzalkonium chloride that is capable of inactivating more than 99% of SARS-CoV-2 particles in one minute of contact, and the life-threatening methicillin-resistant Staphylococcus aureus and Staphylococcus epidermidis (normalized antibacterial halos of 0.52 ± 0.04 and 0.72 ± 0.04, respectively). Nonetheless, despite the results obtained, further studies are needed to ensure the safety and correct use of this technology for the mass production and commercialization of this broad-spectrum antimicrobial face mask filter. Our novel protective non-woven face mask filter would be useful for many healthcare workers and researchers working in this urgent and challenging field. Full article
(This article belongs to the Special Issue Antimicrobial Gels)
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