Super-Resolution Optical Microscopy: Science and Applications

Dear Colleagues,

Super-resolution microscopy stands as a pivotal advancement in biomedical research, enabling the visualization of biological structures beyond the diffraction limit of light. This breakthrough technology has revolutionized our ability to investigate subcellular architectures, molecular interactions, and dynamic processes with unprecedented spatial and temporal resolution. As a highly interdisciplinary field, super-resolution microscopy integrates principles from biology, chemistry, photonics, and computational science to uncover detailed morphological and functional information at the nanoscale.

This Special Issue, titled “Super-Resolution Optical Microscopy: Science and Applications”, invites the submission of high-quality basic, methodological, and applied research contributions, in the form of regular and review articles, focusing on

• The development and validation of novel super-resolution microscopy techniques;
• The study of photophysical and photochemical mechanisms underlying super-resolution, including probe design, labeling strategies, and optical manipulation;
• The integration of multimodal, multispectral, or correlative approaches to enhance resolution, contrast, and functional insight;
• The application and validation of super-resolution methods in preclinical and clinical settings, particularly in understanding pathological changes at the molecular level.

We welcome contributions that highlight both technological innovations and transformative biological or medical applications, aiming to bridge the gap between fundamental research and practical implementation in healthcare.

Dr. Donghan Ma
Dr. Fan Xu
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Photonics is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.