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Special Issue "Powder Processing in Pharmaceutical Applications"
A special issue of Pharmaceutics (ISSN 1999-4923).
Deadline for manuscript submissions: 29 February 2020.
Interests: research on production, tailoring, formulation of nano and micro sized particles and their use for the design of structured products like battery electrodes, drugs and nano composites
In all production processes of solid dosage forms, powders with a multitude of distributed properties must be processed. Starting with the handling for dispensing and weighing, over blending, dosing, comminution, and granulation, up to capsule filling or tableting, powder properties crucially determine the process performance and product quality. In any case, each powder in pharmaceutical formulations brings along distributions of various microscopic properties such as particle size, morphology, and surface energies as well as macroscopic properties such as flow behavior and bulk densities. Along the process chain, multiple powders are blended or more fundamentally change their properties, e.g. by granulation, causing complex changes that will affect their behavior in subsequent processes. Additionally, transportation and packaging of intermediates and final products can cause changes due to aeration, abrasion, or compaction. The determination of powder properties such as particle, surface, and flow properties require sophisticated, methodologic approaches to measure meaningful parameters under representative conditions. The deep knowledge of powder properties and quick and reliable measurement techniques become a prerequisite in the context of continuous process chains that need to immediately respond to material property changes to keep processes and product quality stable within specified ranges. To achieve this, well-developed model approaches need to be derived to predict and control any complex powder processing operation.
This special issue is dedicated to in-depth studies and reviews, presenting fundamental advancement in the scientific field of powder processing in pharmaceutical applications. Contributions addressing thorough insight into unit operations, innovative measurement methods for powder properties, model approaches providing prediction of effects such as demixing, segregation, overmixing, abrasion, deagglomeration, particle breakage, and residence time distribution based on material properties and process parameters, as well as research on continuous process chains are especially encouraged.
Prof. Dr. Arno Kwade
Dr. Jan Henrik Finke
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Pharmaceutics is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- Powder processing/handling
- Process modelling
- Powder properties
- Flow behavior
- Process performance
- Continuous processes
- Capsule filling