Improving the Bioavailability and Solubility of Pharmaceutical Formulations

Dear Colleagues,

In modern pharmacotherapy, there is an increasing demand to develop new pharmaceutical forms that can be safely administered with adequate bioavailability and patient compliance in order to achieve successful therapeutic responses. Bioavailability is essential in the development of new drugs and formulations. More effective and efficient active ingredients can be designed by understanding the factors that affect bioavailability, such as solubility, chemical stability, and pharmaceutical forms. This leads to innovative drugs with higher bioavailability and a better therapeutic profile. In order to reach the site of action and achieve the required pharmacological effect, drugs have to face biological membranes, regardless of the route of administration. Overall, many methods and innovative dosage forms have been developed in the last decade to overcome these challenges.

This Special Issue aims to highlight the key aspects of recent techniques and methods used to improve the bioavailability of active pharmaceutical ingredients, as well as enhance the solubility and dissolution of poorly soluble pharmacons. In this Special Issue, we welcome researchers to contribute original research and review articles relevant to this topic.

We look forward to receiving your contributions.

Dr. Zoltan Ujhelyi
Dr. Dóra Kósa
Dr. Ágota Pető
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Pharmaceutics is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• bioavailability enhancement
• drug delivery systems
• in vitro and in vivo evaluation methods
• therapeutic effectiveness
• pharmaceutical innovations
• nanoformulations
• surfactants
• poorly soluble drugs