Natural Antioxidants from Medicinal Plants: Extraction and Bioactivity

A special issue of Pharmaceuticals (ISSN 1424-8247). This special issue belongs to the section "Natural Products".

Deadline for manuscript submissions: 20 March 2026 | Viewed by 144

Special Issue Editors


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Guest Editor
Department of Pharmaceutical Sciences, Faculty of Sciences, Universidad Católica del Norte, Angamos 0610, Antofagasta, Chile
Interests: phytochemistry; medicinal plants; natural products; pharmacognosy; ethnobotany; antioxidants; antimicrobials; anti-inflammatories; cell culture

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Guest Editor
Department of Pharmacognosy and Pharmaceutical Botany, Faculty of Pharmacy in Hradec Kralove, Charles University, Akademika Heyrovského 1203, 500 05 Hradec Kralove, Czech Republic
Interests: isolation; natural products from medicinal plants; essential oils; ethnopharmacology; anticancer activity; antimicrobial activity

Special Issue Information

Dear Colleagues,

Oxidative stress is a significant contributor to many chronic diseases, including cardiovascular and neurodegenerative disorders. Antioxidants play a vital role in protecting the body by neutralizing harmful free radicals, and while synthetic agents are widely used, there is growing interest in natural alternatives due to their safety and therapeutic potential.

Medicinal plants provide a valuable source of bioactive compounds—such as polyphenols, flavonoids, and terpenoids—that not only scavenge free radicals but also modulate molecular targets and signaling pathways relevant to drug discovery. Advances in extraction and characterization, combined with approaches like structure–activity relationship (SAR) studies, molecular modeling, and pharmacological assays, have strengthened our understanding of their mechanisms of action. Furthermore, insights into pharmacokinetics, pharmacodynamics, and innovative delivery systems are expanding the translational value of these natural products.

This Special Issue, titled “Natural Antioxidants from Medicinal Plants: Extraction and Bioactivity,” welcomes contributions addressing extraction techniques, structural elucidation, bioactivity evaluation, and therapeutic applications, with the goal of inspiring new strategies in the development of antioxidant-based interventions.

Prof. Dr. Julio Escalona-Arranz
Dr. Jesús García-Díaz
Guest Editors

Manuscript Submission Information

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Keywords

  • natural antioxidants
  • medicinal plants
  • extraction methods
  • bioactivity
  • phenolic compounds
  • free radical scavenging
  • pharmacological potential
  • in silico and in vitro correlation
  • molecular modeling

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