Biological Properties of Nanostructures Incorporated in Polymeric Matrices

A special issue of Pharmaceuticals (ISSN 1424-8247). This special issue belongs to the section "Pharmaceutical Technology".

Deadline for manuscript submissions: 22 February 2026 | Viewed by 15

Special Issue Editor


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Guest Editor
1. Laboratory of Clinical Microbiology, Keizo Asami Institute (iLIKA), Federal University of Pernambuco (UFPE), Recife 50670-901, Brazil
2. Laboratory of Microbiology and Immunology, Academic Center of Vitória (CAV), Federal University of Pernambuco (UFPE), Recife 55608-680, Brazil
Interests: nanotechnology; antimicrobial resistance; cancer; diseases; drugs; biotechnology
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Special Issue Information

Dear Colleagues,

The integration of nanostructures into polymeric matrices represents a rapidly advancing frontier in pharmaceutical and biomedical sciences. These hybrid systems offer unique advantages for improving therapeutic efficacy, enhancing biocompatibility, and enabling controlled and targeted delivery. This Special Issue of Pharmaceuticals invites high-quality original research articles, reviews, and short communications that address recent advances and emerging strategies in the design, characterization, and biological evaluation of nanostructure–polymer composites.

We particularly welcome interdisciplinary contributions that focus on the interactions of such systems with biological environments, their functional performance, and their potential for clinical translation.

Topics of interest include, but are not limited to, the following:

  • Smart polymeric nanocomposites responsive to pH, redox, temperature, or enzymatic stimuli;
  • Polymeric nanocarriers for gene delivery, including siRNA, miRNA, and CRISPR-Cas9 systems;
  • Antimicrobial nanostructures targeting biofilm-associated infections and drug-resistant pathogens;
  • Immunomodulatory effects and biocompatibility of nanostructured polymer matrices;
  • Polymersomes and hybrid nanostructures for multifunctional therapeutic applications;
  • Tissue engineering scaffolds with nanostructure-enhanced regenerative potential;
  • Natural compound-loaded polymeric nanocarriers for improved bioavailability and activity;
  • Intranasal and pulmonary delivery platforms for systemic or CNS-targeted therapies;
  • Cancer theranostics, combining diagnostic imaging and therapy in polymer-based nanoplatforms;
  • Three-dimensional bioprinting of polymeric nanostructures for customized biomedical constructs;
  • Green synthesis and sustainable materials in nanostructure–polymer systems;
  • Blood–brain barrier-penetrating nanocarriers for neurological applications;
  • Long-acting injectable formulations for chronic disease management;
  • Nanotoxicology and safety assessment, including advanced in vitro and in vivo models;
  • Artificial intelligence and machine learning in the design and optimization of polymeric nanostructures.

We encourage submissions that utilize novel methodologies, provide mechanistic insights, or demonstrate translational relevance. All manuscripts will be peer-reviewed according to the standards of Pharmaceuticals and published upon acceptance.

Dr. Isabella Macário Ferro Cavalcanti
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Pharmaceuticals is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • antimicrobial resistance
  • cancer
  • diseases
  • nanotechnology
  • polimer

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Published Papers

This special issue is now open for submission.
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