Multi-Targeted Natural Products as Therapeutics, 2nd Edition
A special issue of Pharmaceuticals (ISSN 1424-8247). This special issue belongs to the section "Natural Products".
Deadline for manuscript submissions: 30 September 2026 | Viewed by 932
Special Issue Editors
Interests: effectiveness and safety of natural products; herbal-drug interactions; pediatric clinical pharmacology
Special Issues, Collections and Topics in MDPI journals
Interests: clinical pharmacology; clinical toxicology; pharmacometrics; pediatric pharmacology; maternal-fetal pharmacology; population pharmacokinetics; interventional trials; optimal trial design
Special Issues, Collections and Topics in MDPI journals
Interests: effectiveness and safety of natural products; herbal-drug interactions; pediatric clinical pharmacology
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
For centuries, humans have used medicinal herbs and other natural products to treat and prevent various diseases. In the 20th century, many new drugs, approved by regulatory agencies worldwide, had been isolated from natural products, demonstrating the importance of medicinal herbs and other natural products as a valuable resource in drug development.
Nowadays, we are aware that the pathogenesis of many diseases is multifactorial. Therefore, for the successful treatment and management of these diseases, we should target multiple pathways. Conventional drugs, which are single-molecule medicines, usually target a single pathway or specific body function. Unlike conventional drugs, traditional medicine traditionally uses one or more natural product to prepare extracts, infusions, and decoctions. Preparations using even one medicinal herb may contain hundreds, if not thousands, of bioactive molecules. These molecules target functions of different organs and systems and potentiate or antagonize the functions of the preparation's other bioactive molecules. For example, many, if not all, antibacterial and antiviral drugs also possess immunomodulatory properties. Another example is that anti-cancer remedies may activate or suppress various pathways involved in cancer development and progression.
The Special Issue “The 20th Anniversary of Pharmaceuticals—Multi-Targeted Natural Products as Therapeutics” has enjoyed great success, with 25 articles published. This Special Issue aimed to summarize and examine the latest research findings in identifying natural products targeting multiple pathways and body functions to successfully treat multifactorial diseases. As of September 2025, articles published in this Special Issue had been cited 189 times. It appears that there is considerable interest in investigating the effects of purified extracts prepared from natural products or bioactive molecules from these extracts. We as Guest Editors hope that the second edition of the Special Issue will be successful, and we welcome our colleagues in this field to be part of it through the publication of research results.
Dr. Elena Y. Enioutina
Prof. Dr. Catherine M. T. Sherwin
Dr. Kathleen M. Job
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Pharmaceuticals is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- natural products
- medicinal herbs
- marine products
- animal products
- bioactive compounds
- multifactorial diseases
- multi-targeting phytochemicals
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