Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
5.1
3.7
Journals
Pathogens
Special Issues
Porcine Coronaviruses Infection
share announcement

Porcine Coronaviruses Infection

A special issue of Pathogens (ISSN 2076-0817). This special issue belongs to the section "Viral Pathogens".

Deadline for manuscript submissions: closed (31 May 2023) | Viewed by 3072

Special Issue Editor

Dr. Gun Temeeyasen

E-Mail Website
Guest Editor
Department of Veterinary and Biomedical Sciences, South Dakota State University, Brookings, SD 57007, USA
Interests: porcine coronaviruses; porcine circoviruses; senecavirus A; emerging viruses

Special Issue Information

Dear Colleagues,

In recent decades, porcine coronaviruses (CoVs) have become one of the important pathogens that threaten the swine industry worldwide. These large single-stranded RNA viruses can cause a wide spectrum of diseases affecting the digestive tract, respiratory tract, and nervous system. To date, six CoVs, namely transmissible gastroenteritis virus (TGEV), porcine respiratory coronavirus (PRCV), porcine epidemic diarrhea virus (PEDV), porcine deltacoronavirus (PDCoV), porcine hemagglutinating encephalomyelitis virus (PHEV), and swine acute diarrhea syndrome coronavirus (SADS-CoV) are known as the swine pathogens. From these, PEDV, PDCoV, and SADS-CoV are considered novel CoVs that are of interest to the scientific community. Sequence analyses have demonstrated that these viruses might have transmitted across species, from bat CoV (PEDV and SADS-CoV) and sparrow CoV (PDCoV). Despite extensive studies on this topic in the past decade, the mechanism of disease, host-virus interaction, and the genetic evolution of these porcine CoVs are not fully understood.    

In this Special Issue, we will focus on general topics covering porcine CoVs infection. There is no limitation on the types of contributions; original articles, brief communications, case reports, and reviews are welcome. The scope includes, but is not limited to, pathogenesis, molecular mechanisms, host-virus interactions, genetic evolution, epidemiological studies, vaccine development and evaluation, and novel diagnostic methods of porcine CoVs infections.

Dr. Gun Temeeyasen
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Pathogens is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • porcine coronaviruses
  • pathogenesis
  • molecular mechanisms
  • host-virus interactions
  • genetic evolution
  • epidemiology
  • vaccines
  • diagnostics

Published Papers (2 papers)

Download All Papers
Order results
Result details
Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:

Research

10 pages, 2998 KiB  
Communication
Genetic Characterization and Evolution of Porcine Deltacoronavirus Isolated in the Republic of Korea in 2022
by Hye-Ryung Kim, Jonghyun Park, Kyoung-Ki Lee, Hye-Young Jeoung, Young S. Lyoo, Seung-Chun Park and Choi-Kyu Park
Pathogens 2023, 12(5), 686; https://doi.org/10.3390/pathogens12050686 - 07 May 2023
Viewed by 1395
Abstract
Porcine deltacoronavirus (PDCoV) is an emerging coronavirus that causes diarrhea in nursing piglets. Since its first outbreak in the United States in 2014, this novel porcine coronavirus has been detected worldwide, including in Korea. However, no PDCoV case has been reported since the [...] Read more.
Porcine deltacoronavirus (PDCoV) is an emerging coronavirus that causes diarrhea in nursing piglets. Since its first outbreak in the United States in 2014, this novel porcine coronavirus has been detected worldwide, including in Korea. However, no PDCoV case has been reported since the last report in 2016 in Korea. In June 2022, the Korean PDCoV strain KPDCoV-2201 was detected on a farm where sows and piglets had black tarry and watery diarrhea, respectively. We isolated the KPDCoV-2201 strain from the intestinal samples of piglets and sequenced the viral genome. Genetically, the full-length genome and spike gene of KPDCoV-2201 shared 96.9–99.2% and 95.8–98.8% nucleotide identity with other global PDCoV strains, respectively. Phylogenetic analysis suggested that KPDCoV-2201 belongs to G1b. Notably, the molecular evolutionary analysis indicated that KPDCoV-2201 evolved from a clade different from that of previously reported Korean PDCoV strains and is closely related to the emergent Peruvian and Taiwanese PDCoV strains. Furthermore, KPDCoV-2201 had one unique and two Taiwanese strain-like amino acid substitutions in the receptor-binding domain of the S1 region. Our findings suggest the possibility of transboundary transmission of the virus and expand our knowledge about the genetic diversity and evolution of PDCoV in Korea. Full article
(This article belongs to the Special Issue Porcine Coronaviruses Infection)
►▼ Show Figures

Figure 1

12 pages, 3409 KiB  
Article
Magnolol, a Neolignan-like Drug, Inhibits Porcine Epidemic Diarrhea Virus Replication in Cultured Cells
by Xiaoting Wang, Bingqing Chen, Ruisong Yu, Fusheng Si, Chunfang Xie, Zhen Li, Shijuan Dong and Daojing Zhang
Pathogens 2023, 12(2), 263; https://doi.org/10.3390/pathogens12020263 - 06 Feb 2023
Cited by 1 | Viewed by 1128
Abstract
Porcine epidemic diarrhea virus (PEDV) is a destructive pathogen that continues to adversely affect the swine industry worldwide due to a current lack of vaccines and drugs capable of effective disease control. In the present study, the neolignan-like drug, magnolol (MAG), was tested [...] Read more.
Porcine epidemic diarrhea virus (PEDV) is a destructive pathogen that continues to adversely affect the swine industry worldwide due to a current lack of vaccines and drugs capable of effective disease control. In the present study, the neolignan-like drug, magnolol (MAG), was tested for its ability to inhibit a Vero-cell adapted PEDV strain DR13att. Our data revealed that MAG exhibited anti-PEDV activity in vitro, with IC50 and CC50 values of 28.21 μM and 57.28 μM, respectively. MAG was an efficient inhibitor of viral replication, and repression of viral proliferation was strongest when the host cells were exposed to MAG and the virus at the same time. Although our data indicate that MAG has the potential to be a useful PEDV control agent, in vivo testing of the drug, using animal hosts, is required. Full article
(This article belongs to the Special Issue Porcine Coronaviruses Infection)
►▼ Show Figures

Figure 1

Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:
 
Displaying articles 1-2
Back to TopTop