Special Issue "Bovine Viral Diarrhea virus"
A special issue of Pathogens (ISSN 2076-0817).
Deadline for manuscript submissions: closed (30 November 2017).
2. School of Chemistry and Molecular Biosciences, The University of Queensland, St. Lucia, Qld 4072, Australia.
3. School of Veterinary Medicine, The University of Queensland, Gatton Campus, Qld 4343, Australia.
Interests: infectious diseases pathobiology; viral persistence; flaviviruses; transplacental virus infections; co-infections; viral zoonoses; arbo-viruses; influenza viruses
Special Issues and Collections in MDPI journals
It has been 70 years since the first description of bovine viral diarrhea virus (BVDV)—in 1946—and major progress has been made in elucidating the pathogenesis of this world-wide important infection of ruminants. Likewise, understanding of the virus biology has seen incremental advances and significant strides in the interphase of basic virology and pathobiology to advance our understanding of this fascinating virus and the disease spectrum it can cause. While BVDV remains a significant concern for the cattle industry, the food supply and the agricultural economy world-wide and much research effort rightfully has gone into epidemiology, diagnostics and prevention—and continues to do so—BVDV has also served as an excellent model for understanding mechanisms in RNA-virus biology, transplacental virus infection, and host responses to persistent virus infection—and the interphase of all of these aspects and more. However, there remains so many questions to be addressed in exactly those very same areas, including the conditions, at both the cellular and organismic level, that are conducive to events leading to the biotype-switch from a non-cytopathic to a cytopathic virus, the discrepancies between in vitro and in vivo results for interferon induction by and effect on BVDV and the animal as a whole, and the characterization of the state of “tolerance” in persistently infected animals—to mention just a few.
The Special Issue on ‘Bovine Viral Diarrhea Virus (BVDV)’ will focus on the current status of our understanding of the biology of the virus, the virus–host interactions leading to different clinical outcomes, mechanisms of viral persistence, recombination events leading to biotype change of these viruses and developments in vaccine development and other control mechanisms.
Dr. Helle Bielefeldt-Ohmann
Manuscript Submission Information
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- Bovine viral diarrhea virus
- mucosal disease
- viral persistence
- host-virus interaction
- transplacental transmission
- viral replication