Advanced Research on Vaccine Development for Infectious Diseases
A special issue of Pathogens (ISSN 2076-0817). This special issue belongs to the section "Vaccines and Therapeutic Developments".
Deadline for manuscript submissions: closed (31 October 2023) | Viewed by 2268
Special Issue Editors
Interests: animal virus; vaccines; transboundary diseases
Special Issue Information
Dear Colleagues,
Vaccination stands among the most decisive public health interventions in human history. Such an achievement is not only due to vaccines applied to the human population but also to those developed for animal health.
The most ancient records of prophylactic approaches for the immune prevention of infectious diseases are those related to the smallpox treatment in China and India between five and ten centuries ago. Following the same line, Jenner’s publications at the end of the 18th century, showing how experimental infections with cowpox may prevent or ameliorate further smallpox infections, could represent the onset of vaccinology as the science of vaccine development.
Different milestones stand out along this long journey from those rather rudimentary but pioneering approaches to modern vaccines: the development of bacterial culture techniques, the ability to produce in vitro viruses in tissue cultures, and new strategies applied from the molecular biology and advanced chemistry perspectives. As a result, an enormous array of vaccination strategies emerged, significantly improving the sanitary situation at a global scale within the One Health perspective.
This Special Issue will focus on original reports and reviews investigating the generation of novel vaccines against infectious agents and new approaches for evaluating vaccine-induced immune responses. Potential topics related to human and animal vaccinology include, but are not limited to, the following:
- Reverse genetics applied to vaccine development;
- New antigen delivery strategies, including vectored and nucleic acid-based vaccines, nanoparticles and immunostimulant complexes;
- New adjuvants and immunostimulatory strategies;
- Rationally designed live attenuated vaccines;
- Systems immunology applied to vaccine development and evaluation.
Dr. Mariano Pérez-Filgueira
Dr. Alejandra Capozzo
Guest Editors
Manuscript Submission Information
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Keywords
- recombinant vaccines
- production platforms
- protection
- antigen delivery
- adjuvants
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