10th Anniversary of Pathogens—Advances in Molecular and Cellular Parasitology

A special issue of Pathogens (ISSN 2076-0817). This special issue belongs to the section "Parasitic Pathogens".

Deadline for manuscript submissions: closed (25 October 2022) | Viewed by 3319

Special Issue Editor


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Guest Editor
Inserm, University of Montpellier, 34095 Montpellier, France
Interests: cellular parasitology; Apicomplexa; Toxoplasma; autophagy; metabolism; cell biology
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The year 2022 marks the 10th anniversary of the publication of Pathogens. We would like to express our sincerest thanks to our readers, innumerable authors, anonymous peer reviewers, editors, and all the people working in one way or another for the journal, who have made substantial contributions over the years. We are delighted and proud to celebrate this milestone with a series of Special Issues and events.

A Special Issue entitled “10th Anniversary of Pathogens—Advances in Molecular and Cellular Parasitology” will be launched as a part of this celebration. This is intended to be a collection of high-quality research articles and reviews focusing on the molecular and cellular mechanisms underlying parasite-caused diseases. Topics covered in this Special Issue include new insights into the molecular and cellular features of host/parasite interactions, understanding the immunological background of parasitic diseases, basic research findings that may translate into therapeutic opportunities, and finally recent technical advances can also be covered when they contribute to a better understanding of important molecular mechanisms and cellular aspects of parasitic diseases.

Dr. Sébastien Besteiro
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Pathogens is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • parasitic diseases
  • molecular and cellular features
  • host/parasite interaction
  • technical advances

Published Papers (1 paper)

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Review

13 pages, 1020 KiB  
Review
Recent Advances in the Immunologic Method Applied to Tick-Borne Diseases in Brazil
by Mônica E. T. Alcon-Chino and Salvatore G. De-Simone
Pathogens 2022, 11(8), 870; https://doi.org/10.3390/pathogens11080870 - 2 Aug 2022
Cited by 1 | Viewed by 2756
Abstract
Zoonotic-origin infectious diseases are one of the major concerns of human and veterinary health systems. Ticks, as vectors of several zoonotic diseases, are ranked second only to mosquitoes as vectors. Many ticks’ transmitted infections are still endemic in the Americas, Europe, and Africa [...] Read more.
Zoonotic-origin infectious diseases are one of the major concerns of human and veterinary health systems. Ticks, as vectors of several zoonotic diseases, are ranked second only to mosquitoes as vectors. Many ticks’ transmitted infections are still endemic in the Americas, Europe, and Africa and represent approximately 17% of their infectious diseases population. Although our scientific capacity to identify and diagnose diseases is increasing, it remains a challenge in the case of tick-borne conditions. For example, in 2017, 160 cases of the Brazilian Spotted Fever (BSF, a tick-borne illness) were confirmed, alarming the notifiable diseases information system. Conversely, Brazilian borreliosis and ehrlichiosis do not require notification. Still, an increasing number of cases in humans and dogs have been reported in southeast and northeastern Brazil. Immunological methods applied to human and dog tick-borne diseases (TBD) show low sensitivity and specificity, cross-reactions, and false IgM positivity. Thus, the diagnosis and management of TBD are hampered by the personal tools and indirect markers used. Therefore, specific and rapid methods urgently need to be developed to diagnose the various types of tick-borne bacterial diseases. This review presents a brief historical perspective on the evolution of serological assays and recent advances in diagnostic tests for TBD (ehrlichiosis, BSF, and borreliosis) in humans and dogs, mainly applied in Brazil. Additionally, this review covers the emerging technologies available in diagnosing TBD, including biosensors, and discusses their potential for future use as gold standards in diagnosing these diseases. Full article
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