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Nutrients
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Clinical Nutrition and Hydration in Older People
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Clinical Nutrition and Hydration in Older People

A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Geriatric Nutrition".

Deadline for manuscript submissions: 15 October 2025 | Viewed by 6750

Special Issue Editor

Prof. Dr. Susana Sánchez-Fidalgo

E-Mail Website
Guest Editor
1. Department of Preventive Medicine and Public Health, University of Seville, Av. Sanchez Pizjuan s/n, 41009 Seville, Spain
2. ChronicPharma: Study Group for the Optimization of Pharmacotherapy in Chronic Patients—CTS-1077, Public Health System of Andalusia, Andalusian Public Foundation for the Management of Health Research of Seville (FISEVI), Seville, Spain
Interests: multimorbidity; chronic patients; polypharmacy; anticholinergic effects; deprescription; adherence; inflammation; immunologic disorders
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Older people are particularly vulnerable to malnutrition and dehydration, which can significantly affect their health and quality of life. Due to advanced age, their bodies undergo changes that can affect their ability to absorb nutrients and maintain proper hydration, leading to reduced dietary intake in combination with catabolic disease effects. Malnutrition and dehydration in the elderly often result in serious health consequences, including risk of mortality, and are considered important factors contributing to the complex etiology of sarcopenia and frailty.

Preventing malnutrition and dehydration is essential to maintaining health in this vulnerable population.

The aim of this Special Issue is to deliver novel insights into the risk factors associated with malnutrition and dehydration and strategies for prevention in elderly people.

Prof. Dr. Susana Sánchez-Fidalgo
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nutrients is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • nutrition
  • hydration
  • elderly
  • chronicity
  • prevention
  • health public
  • risk factors

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Published Papers (2 papers)

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14 pages, 477 KB  
Article
Hydration Status in Geriatric Patients—Subjective Impression or Objective Parameter? The Hydr-Age-Study
by Linda Deissler, Matthias Janneck, Rainer Wirth, Alexander Fierenz, Ulrich Thiem and Alexander Rösler
Nutrients 2025, 17(19), 3129; https://doi.org/10.3390/nu17193129 - 30 Sep 2025
Viewed by 188
Abstract
Background/Objectives: Assessing the hydration status (HS) in geriatric patients remains challenging due to multimorbidity, polypharmacy, and cognitive impairment. Common indicators like reduced skin turgor and dry mucous membranes are unreliable. The Hydr-Age-Study is a prospective observational pilot study with a post hoc analysis [...] Read more.
Background/Objectives: Assessing the hydration status (HS) in geriatric patients remains challenging due to multimorbidity, polypharmacy, and cognitive impairment. Common indicators like reduced skin turgor and dry mucous membranes are unreliable. The Hydr-Age-Study is a prospective observational pilot study with a post hoc analysis to evaluate the diagnostic accuracy of clinical, laboratory, and instrumental methods to assess HS in hospitalised older adults. Methods: Upon admission, patients underwent an assessment including their medical history, a clinical evaluation, laboratory tests, ultrasound examination, and bioimpedance analysis. These data were collected and independently reviewed by two experts who diagnosed each patient’s current HS. This diagnosis served as the clinical reference standard for evaluating the diagnostic accuracy of each method. Results: Twenty-six methods were examined, of which four achieved an AUC > 0.8. Axillary dryness showed a high diagnostic accuracy for hypohydration (AUC = 0.854), with a sensitivity of 83.3% and a specificity of 82.8%. Inferior vena cava (IVC) ultrasound effectively detected both hypo- and hyperhydration. A subxiphoid IVC diameter ≤ 1.95 cm identified hypohydration with 90.9% sensitivity and 50.6% specificity. For hyperhydration, a diameter of ≥2.15 cm provided strong diagnostic performance in both subxiphoid and transcostal views. Conclusions: Axillary dryness and IVC sonography demonstrated the highest diagnostic accuracy. No other methods exceeded an AUC of 0.80. In the absence of a gold standard, a structured clinical consensus provides a feasible and reproducible approach to establish a clinical reference standard. These findings may contribute to the development of a standardised assessment protocol in geriatric medicine. Full article
(This article belongs to the Special Issue Clinical Nutrition and Hydration in Older People)
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Review

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25 pages, 1569 KB  
Review
Hydration Strategies in Older Adults
by Jacquelyn Pence, Allyson Davis, Ebonie Allen-Gregory and Richard J. Bloomer
Nutrients 2025, 17(14), 2256; https://doi.org/10.3390/nu17142256 - 8 Jul 2025
Cited by 1 | Viewed by 6203
Abstract
Hydration is the body’s ability to absorb water and to maintain the correct balance of fluid and electrolytes and is essential to human health. Dehydration can adversely affect metabolism, thermoregulation, digestion, and neurological, kidney, and heart function. Aging as well as disease and [...] Read more.
Hydration is the body’s ability to absorb water and to maintain the correct balance of fluid and electrolytes and is essential to human health. Dehydration can adversely affect metabolism, thermoregulation, digestion, and neurological, kidney, and heart function. Aging as well as disease and medications affect water and electrolyte levels in the body and can lead to dehydration in older adults. In this review, we discuss factors contributing to dehydration in older adults, how hydration is measured, and strategies to improve hydration status. We close with a summary of the different areas of focus related to hydration research. Full article
(This article belongs to the Special Issue Clinical Nutrition and Hydration in Older People)
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