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New Perspective on Nutrient Intake and Cardiovascular Disease Risk

A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Nutritional Epidemiology".

Deadline for manuscript submissions: 15 October 2026 | Viewed by 1525

Special Issue Editor


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Guest Editor
Department of Epidemiology and Biostatistics, Dornsife School of Public Health, Drexel University, Philadelphia, PA, USA
Interests: global health in chronic disease and mhealth; cardiometabolic disorders and health disparities; neurodevelopment and neurologic disorders; pharmacoepidemiology; heart failure epidemiology; AI/machine learning-enabled risk prediction models

Special Issue Information

Dear Colleagues,

This Special Issue aims to present new perspectives on how nutrient intake, assessed through advanced measurement tools and analyzed using cutting-edge statistical and artificial intelligence (AI)/machine learning, influences cardiovascular disease risk. Topics of interest include heart failure (including HFrEF, HFmrEF, and HFpEF), stroke (ischemic and hemorrhagic), and peripheral arterial disease. We welcome high-quality original research articles, review papers, and novel methodological studies that expand our understanding of diet-related cardiovascular health through innovative conceptual frameworks and longitudinal analytical approaches.

Dr. Longjian Liu
Guest Editor

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Keywords

  • nutrient intake
  • novel and advanced dietary patterns (e.g., reduced rank regression [RRR], principal component analysis [PCA], cluster analysis)
  • inflammatory and metabolic pathways linking nutrients to cardiovascular outcomes
  • metabolomics and nutritional biomarkers
  • diet–aging interactions
  • vascular and biological age metrics
  • nutrient–gene interactions and epigenetics in cardiovascular disease risk
  • mediation, interaction, and causal inference in nutritional epidemiology
  • risk prediction modeling
  • AI/machine learning methods
  • large-scale prospective cohort studies
  • large-scale randomized clinical trials
  • large-scale electronic health records and claims data

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Published Papers (1 paper)

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Research

17 pages, 727 KB  
Article
Blood Pressure Control Is Associated with Moderate, but Not Necessarily High, Adherence to the DASH Diet in Older Adults
by Rafael Luengo-Dilla, Adriana Ortega-Hernández, Mónica Álvarez-González, Javier Gutiérrez-Corral, Javier Modrego, Macarena Torrego-Ellacuría, Sergio de la Torre-Rodríguez, Imane Jeidane-Bentefrit, Julia García-García, María Soledad Fragua-Gil, Dulcenombre Gómez-Garre, Arturo Corbatón-Anchuelo and The SEGOVIA Study Group
Nutrients 2026, 18(2), 334; https://doi.org/10.3390/nu18020334 - 20 Jan 2026
Viewed by 1179
Abstract
Background/Objectives: Hypertension control remains a global challenge. Evidence on the association between adherence to the Dietary Approaches to Stop Hypertension (DASH) diet and blood pressure (BP) control in older Mediterranean populations is limited. We aimed to assess this association in Spanish older adults. [...] Read more.
Background/Objectives: Hypertension control remains a global challenge. Evidence on the association between adherence to the Dietary Approaches to Stop Hypertension (DASH) diet and blood pressure (BP) control in older Mediterranean populations is limited. We aimed to assess this association in Spanish older adults. Methods: This cross-sectional analysis included 371 participants (69 ± 9 years). Dietary intake was assessed using a validated 146-item food frequency questionnaire (FFQ), and DASH diet adherence was categorized as low, medium, or high. Multivariable logistic regression models were used to examine associations with BP control. Results: Among participants with hypertension (n = 218), 52.8% achieved adequate BP control and consumed significantly more low-fat dairy products (+56%) and less sodium (−11%) than those with uncontrolled BP. The low adherence group had lower proportion of participants with controlled BP (21%) than the medium and high adherence groups (36% and 39%, respectively) (p < 0.05). Across increasing DASH diet adherence categories, systolic blood pressure (SBP) and diastolic blood pressure (DBP) were 4–5 mmHg and 3–4 mmHg lower, respectively. Medium adherence to the DASH diet was independently associated with substantially lower odds of uncontrolled BP (OR = 0.37; 95% CI: 0.16–0.82; p = 0.015). High adherence showed a similar magnitude of association but did not reach statistical significance. Conclusions: In this cohort of older Spanish adults, moderate adherence to the DASH diet was associated with meaningful improvements in BP control, suggesting that achievable, intermediate levels of DASH diet adherence may be sufficient to improve hypertension management in real-world settings. Longitudinal studies are needed to confirm causality and long-term cardiovascular benefits. Full article
(This article belongs to the Special Issue New Perspective on Nutrient Intake and Cardiovascular Disease Risk)
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