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Nutrients
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Diet, Physical Activity and Lifestyle Interventions for People with Mental...
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Diet, Physical Activity and Lifestyle Interventions for People with Mental Health Conditions

A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Nutrition and Public Health".

Deadline for manuscript submissions: 25 December 2025 | Viewed by 407

Special Issue Editors

Dr. Mohammadreza Mohebbi

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Guest Editor
Associate Professor, Biostatistics Unit, Faculty of Health, Deakin University, Geelong, Australia
Interests: biostatistics; epidemiology; mental health; nutrition
Dr. Mojtaba Lotfaliany

E-Mail Website
Guest Editor
IMPACT—The Institute for Mental and Physical Health and Clinical Translation, Food & Mood Centre, School of Medicine, Barwon Health, Deakin University, Geelong, VIC 3220, Australia
Interests: clinical sciences; public health; epidemiology; nutrition and dietetics; health services and systems

Special Issue Information

Dear Colleagues,

Evidence suggests that modifiable lifestyle factors are crucial in preventing and managing mental health disorders. Adopting healthy habits and making positive changes can improve mental well-being, lower the risk of mental health conditions developing, and manage the progression and symptoms of mental disorders. These lifestyle factors include, but are not limited to, dietary habits, nutrition, physical activity, sleep, social interactions, and substance use. This Special Issue aims to provide an overview of recent advances regarding the role of dietary patterns, nutritional factors, or relevant dietary interventions in mental health. Research that enhances our understanding of how dietary interventions or nutritional factors affect mental health, such as exploring potential pathways and biological mechanisms like chronic low-grade inflammation and the gut-brain axis, or the mediating role of other modifiable lifestyle factors, is within the scope of this Special Issue. We welcome the submission of original articles, reviews, systematic reviews, and meta-analyses to this Special Issue.

Dr. Mohammadreza Mohebbi
Dr. Mojtaba Lotfaliany
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nutrients is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • mental health
  • depressive disorder
  • cognition
  • anxiety
  • mood
  • mental health disorders
  • modifiable risk factors
  • low-grade inflation
  • food intake/dietary intake
  • nutrients
  • physical activity
  • alcohol intake
  • substance use
  • social networking and social isolation

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Published Papers (1 paper)

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Research

15 pages, 771 KiB  
Article
Moderate Alcohol Consumption and Risk of Depression: A Longitudinal Analysis in Community-Dwelling Older Adults
by Mohammadreza Mohebbi, Najmeh Davoodian, Shiva Ganjali, Lawrence J. Beilin, Michael Berk, Malcolm Forbes, John J. McNeil, Mark R Nelson, Joanne Ryan, Rory Wolfe, Robyn L. Woods and Mojtaba Lotfaliany
Nutrients 2025, 17(16), 2688; https://doi.org/10.3390/nu17162688 - 20 Aug 2025
Viewed by 209
Abstract
Background/Objectives: Evidence suggests a J-shaped association between alcohol consumption and depression, but it remains unclear whether this reflects a true causal effect, reverse causation, or methodological bias. This uncertainty is particularly relevant in older adults, who are at increased risk for both depression [...] Read more.
Background/Objectives: Evidence suggests a J-shaped association between alcohol consumption and depression, but it remains unclear whether this reflects a true causal effect, reverse causation, or methodological bias. This uncertainty is particularly relevant in older adults, who are at increased risk for both depression and alcohol-related harms. This study aimed to examine the association between varying levels of alcohol consumption and depression risk in community-dwelling older adults. Methods: We analyzed 16,563 community-dwelling older adults (mean age 75.1 ± 4.6 years) from the ASPirin in Reducing Events in the Elderly (ASPREE) trial. Alcohol intake, reported at baseline and follow-up, was categorized as abstinent, occasional, moderate, or above-guideline. Both intention-to-treat (classified by baseline alcohol consumption, regardless of later changes) and per-protocol (using annual time-updated alcohol consumption ) analyses were performed. To address confounding, informative censoring, and selection bias, we applied marginal structural models with inverse probability weighting. Results: In per-protocol analyses, abstainers (OR 1.17), occasional drinkers (OR 1.11), and above-guideline drinkers (OR 1.15) were significantly associated with a higher risk of depression compared with moderate drinkers, consistent with a J-shaped association. Sensitivity analyses excluding former drinkers and those with baseline depressive symptoms showed similar results. The association remained robust after adjusting for social isolation, social support, social interactions, physical activity, pain, sleep duration, sleep difficulties, and sleep medication use (n = 14,892; Australian sub-sample), and did not differ by sex. Conclusions: Moderate alcohol consumption was associated with the lowest depression risk, confirming a J-shaped relationship after comprehensive confounder adjustment. Full article
(This article belongs to the Special Issue Diet, Physical Activity and Lifestyle Interventions for People with Mental Health Conditions)
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