Nutrition, Lipoprotein Metabolism, and Mechanisms of Atherosclerosis Prevention
A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Lipids".
Deadline for manuscript submissions: 20 October 2026 | Viewed by 68
Special Issue Editor
Interests: mass spectrometry-based proteomics; HDL and lipoprotein function; lipid metabolism; mechanisms of cardiovascular disease; oxidative stress; translational research in human diseases
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Atherosclerosis remains a leading cause of cardiovascular morbidity and mortality worldwide, arising from complex interactions among diet, lipoprotein metabolism, and molecular mechanisms regulating vascular health. Lipids and lipoproteins, particularly high-density lipoproteins (HDL) and low-density lipoproteins (LDL), are central to lipid transport, inflammation, and oxidative stress. Disruptions in lipoprotein metabolism, often influenced by nutritional patterns, can lead to dyslipidemia—a major risk factor for atherosclerosis and cardiovascular disease. Elevated LDL levels, oxidative modification of lipoproteins, and impaired reverse cholesterol transport are key drivers of plaque formation and vascular inflammation, whereas certain dietary components and metabolic pathways can enhance HDL function, reduce lipid accumulation, and protect against disease.
Despite extensive research, many mechanistic links between nutrition, lipoprotein function, and atherosclerosis remain incompletely understood. For this Special Issue, we invite original research and reviews that explore dietary or nutritional interventions, as well as mechanistic, translational, and clinical studies, on lipoprotein functionality, HDL proteomics, biomarkers of cardiovascular risk, and molecular pathways involved in atherogenesis, particularly when these findings are discussed from a nutritional perspective or provide insights that may inform dietary or nutritional recommendations. Contributions from diverse populations and geographic regions are welcome. By integrating molecular insights with clinical and translational perspectives, this Special Issue aims to advance preventive strategies and inform effective nutritional and metabolic interventions to reduce the global burden of cardiovascular disease.
Dr. Baohai Shao
Guest Editor
Manuscript Submission Information
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Keywords
- atherosclerosis
- atherosclerosis prevention
- cardiovascular disease
- cholesterol transport
- dietary interventions
- dyslipidemia
- HDL function
- high-density lipoprotein (HDL)
- inflammation
- lipoprotein metabolism
- low-density lipoprotein (LDL)
- nutrition
- oxidative stress
- proteomics
- lipidomics
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