Special Issue "Plant Sterols/Stanols and Human Health"
A special issue of Nutrients (ISSN 2072-6643).
Deadline for manuscript submissions: closed (1 November 2018)
Prof. Helena Gylling
University of Helsinki and Helsinki University Hospital, Internal Medicine, Helsinki, Finland
Interests: Plant sterol/stanol metabolism in humans; Plant sterils/stanols and cholesterol interplay in humans; Plant sterols/stanols in dyslipidemias; Plant sterols/stanols in atherosclerosis and in cardiovascular diseases
Plant sterols and plant stanols are normal components of plants, which are not synthesized in the humans, so that they are derived from dietary sources. They have gained a lot of interest during the last two decades after foods and supplements with added plant sterols/stanols were launched as effective and safe non-pharmacologic hypocholesterolemic agents, and also after the mechanisms of intestinal absorption and hepatic excretion of cholesterol and plant sterols/stanols were unraveled. Even though ample available research on plant sterols/stanols, there are items not clarified in detail or which are scattered in the original publications. The metabolism of plant sterols/stanols in humans and their role and possible clinical consequencies in parenteral nutrition are examples of topics welcomed to gather the available information scattered at the moment. The main clinical effects of plant sterols/stanols are on circulating lipids, but there is also information on their effects on other atherosclerotic risk factors such as inflammation and fatty liver, so that the topic of dyslipidemias, metabolic syndrome, and fatty liver deals with their role in preventing atherosclerosis. Finally, the effect of dietary fat on the interplay of cholesterol and plant sterols/stanols in intestine is important and has practical consequencies, but is very little dealt with in the literature, and whether plant sterols/stanols accumulate in human tissues and whether they have atherogenic potential are important clinical issues which need objective and detailed examinations. To this end, you are cordially invited to submit proposals for manuscripts that fir the objectives and topics of this Special Issue.Prof. Helena Gylling
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- LDL cholesterol
- HDL cholesterol
- Metabolic syndrome
- Dietary fat
- Plant sterol absorption
- Plant stanol absorption
- Coronary artery disease
- Parenteral nutrition