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Diet on Gut Health and Celiac Disease

A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Nutritional Immunology".

Deadline for manuscript submissions: 25 March 2026 | Viewed by 186

Special Issue Editor


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Guest Editor
Division of Gastroenterology and Hepatology, Graham H Jeffries Professor of Medicine, Department of Medicine, Penn State College of Medicine, Hershey, PA, USA
Interests: inflammatory bowel disease; celiac disease; graduate medical education

Special Issue Information

Dear Colleagues,

The incidence and prevalence of celiac disease is increasing worldwide. There is a growing recognition of the associated challenges with managing celiac disease as well as associated clinical conditions. Associated clinical conditions span the spectrum of bone health, micronutrients and vitamin deficiencies, and other immune-mediated conditions, including diabetes and thyroid disease.

This issue aims to explore the potential role and possible effects of dietary components such as dietary fiber and prebiotics/probiotics on gut health and celiac disease. In addition, we will provide a comprehensive review of updated actions to ensure the quality of treatment, establishing a roadmap to excellent care.

Dr. Kofi Clarke
Guest Editor

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Keywords

  • vitamins
  • micronutrient deficiencies
  • dietary fiber content
  • bone health
  • prebiotics

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Published Papers (1 paper)

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Review

12 pages, 507 KB  
Review
Avoidant/Restrictive Food Intake Disorder in Celiac Disease
by Ridhima Kaul, Claire Jansson-Knodell, Madison L. Simons, Kendra Weekley, David Gardinier and Alberto Rubio-Tapia
Nutrients 2025, 17(20), 3197; https://doi.org/10.3390/nu17203197 (registering DOI) - 11 Oct 2025
Abstract
Celiac disease (CeD) is an autoimmune disorder where adherence to a lifelong gluten-free diet (GFD) is the only available treatment. While this approach is rather effective, some patients experience ongoing symptoms, and this factor, along with the rigidity of the GFD, may predispose [...] Read more.
Celiac disease (CeD) is an autoimmune disorder where adherence to a lifelong gluten-free diet (GFD) is the only available treatment. While this approach is rather effective, some patients experience ongoing symptoms, and this factor, along with the rigidity of the GFD, may predispose some to disordered eating behaviors, including Avoidant/Restrictive Food Intake Disorder (ARFID). ARFID is characterized by persistent food avoidance that is not driven by body image concerns, resulting in nutritional, psychological, and social impairment. This scoping literature review explores the emerging intersection between ARFID and CeD, examining prevalence, pathophysiology, clinical features, complications, and management strategies. Recent studies report that 14–57% of individuals with CeD may meet the criteria for ARFID, depending on the population and screening tools used. Factors contributing to ARFID in CeD may include ongoing gastrointestinal symptoms, anxiety over gluten exposure, negative conditioned responses to food, social challenges related to GFD adherence, and psychiatric co-morbidities. ARFID in CeD is associated with worsened nutritional deficiencies, anxiety, depression, and impaired social functioning, making the diagnosis of ARFID challenging due to symptom overlap with CeD and other psychiatric conditions. Management requires a multidisciplinary approach, including medical, nutritional, and psychological interventions. Routine screening, early intervention, and integrated care models may improve outcomes and quality of life. Full article
(This article belongs to the Special Issue Diet on Gut Health and Celiac Disease)
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