Vitamin D and Age-Related Diseases
A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Micronutrients and Human Health".
Deadline for manuscript submissions: 20 September 2025 | Viewed by 365
Special Issue Editors
Interests: vitamin D; adipose tissue; inflammation; macrophage; Alzheimer’s disease; sarcopenia; aging
Interests: obesity; metabolic disease; vitamin D; adipocyte; inflammation
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Vitamin D plays a crucial role not only in bone health, but also in immune function, inflammation regulation, cardiovascular health, muscle maintenance, and neuroprotection, making it a key factor in aging-related chronic diseases. Many clinical studies have reported associations between vitamin D status and the incidence of metabolic disorders, including type 2 diabetes and atherosclerosis, as well as neurodegenerative diseases such as dementia. However, further research is needed to clarify the molecular mechanisms underlying these associations and to examine the changes in vitamin D levels across different populations.
Additionally, a definition of vitamin D deficiency and sufficiency has not yet been established. While its role in bone health is clear, its broader implications for aging-related diseases call for a reassessment of optimal vitamin D levels. Determining whether vitamin D supplementation can effectively prevent these conditions therefore remains a topic of concern.
This Special Issue aims to achieve the following:
(a) Investigate the role of vitamin D in health and aging, from molecular mechanisms to clinical outcomes;
(b) Assess the impact of vitamin D supplementation on age-related diseases, including type 2 diabetes, atherosclerosis, Alzheimer’s disease, and insulin resistance;
(c) Analyze the association between serum 25-hydroxyvitamin D (25(OH)D) levels, dietary intake, supplementation, and key physiological pathways in older adults;
(d) Review current research on vitamin D metabolism and its relevance to aging-related chronic diseases;
(e) Explore effective strategies to prevent deficiencies and optimize vitamin D status across different life stages.
Dr. Chan Yoon Park
Dr. Eugene Chang
Guest Editors
Manuscript Submission Information
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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- vitamin D status
- vitamin D supplementation
- aging
- vitamin D and metabolic chronic disorders
- vitamin D and neurodegenerative diseases
- vitamin D and inflammation
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