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Nutrients
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High-Fat Diet in High-Risk Population
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High-Fat Diet in High-Risk Population

A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Nutrition and Public Health".

Deadline for manuscript submissions: closed (15 February 2024) | Viewed by 4340

Special Issue Editor

Dr. Jiunn-Ming Sheen

E-Mail Website
Guest Editor
1. Department of Pediatrics, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung 833, Taiwan
2. Graduate Institute of Clinical Medical Science, Chang Gung University College of Medicine, Kaohsiung 833, Taiwan
Interests: nutrition; microbiota; oxidative stress; DOHaD; cancer

Special Issue Information

Dear Colleagues,

A high-fat diet and less physical activity result in a higher energy intake and lower energy expenditure.  High-fat diets, which are frequent related to obesity, are associated with many health problems, including cognition, cardiovascular and metabolic issues, non-alcoholic fatty liver disease and even cancer. However, which populations are most susceptible to the effects of a high-fat diet remain unknown.  In addition, there are many unknown factors that can interact with a high-fat diet. Furthermore, the effects of high-fat diets can be inherited by offspring.

This Special Issue welcomes original research and review articles with clinical, experimental and epidemiological content concerning factors interacting with a high-fat diet and populations at risk for a high-fat diet.

Dr. Jiunn-Ming Sheen
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nutrients is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • high-fat diet
  • obesity
  • microbiota
  • mechanism
  • cancer
  • high risk populations

Published Papers (2 papers)

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Review

23 pages, 1395 KiB  
Review
High Fat Diet and Polycystic Ovary Syndrome (PCOS) in Adolescence: An Overview of Nutritional Strategies
by Valeria Calcaterra, Vittoria Carlotta Magenes, Giulia Massini, Luisa De Sanctis, Valentina Fabiano and Gianvincenzo Zuccotti
Nutrients 2024, 16(7), 938; https://doi.org/10.3390/nu16070938 - 24 Mar 2024
Viewed by 1522
Abstract
Polycystic ovary syndrome (PCOS) is a multifaceted and heterogeneous disorder, linked with notable reproductive, metabolic, and psychological outcomes. During adolescence, key components of PCOS treatment involve weight loss achieved through lifestyle and dietary interventions, subsequently pursued by pharmacological or surgical therapies. Nutritional interventions [...] Read more.
Polycystic ovary syndrome (PCOS) is a multifaceted and heterogeneous disorder, linked with notable reproductive, metabolic, and psychological outcomes. During adolescence, key components of PCOS treatment involve weight loss achieved through lifestyle and dietary interventions, subsequently pursued by pharmacological or surgical therapies. Nutritional interventions represent the first-line therapeutic approach in adolescents affected by PCOS, but different kinds of dietary protocols exist, so it is necessary to clarify the effectiveness and benefits of the most well-known nutritional approaches. We provided a comprehensive review of the current literature concerning PCOS definition, pathophysiology, and treatment options, highlighting nutritional strategies, particularly those related to high-fat diets. The high-fat nutritional protocols proposed in the literature, such as the ketogenic diet (KD), appear to provide benefits to patients with PCOS in terms of weight loss and control of metabolic parameters. Among the different types of KD studies, very low-calorie ketogenic diets (VLCKD), can be considered an effective dietary intervention for the short-term treatment of patients with PCOS. It rapidly leads to weight loss alongside improvements in body composition and metabolic profile. Even though extremely advantageous, long-term adherence to the KD is a limiting factor. Indeed, this dietary regimen could become unsustainable due to the important restrictions required for ketosis development. Thus, a combination of high-fat diets with more nutrient-rich nutritional regimens, such as the Mediterranean diet, can amplify positive effects for individuals with PCOS. Full article
(This article belongs to the Special Issue High-Fat Diet in High-Risk Population)
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20 pages, 1040 KiB  
Review
Maternal High-Fat Diet Controls Offspring Kidney Health and Disease
by Hsi-Yun Liu, Chen-Hao Lee, Chien-Ning Hsu and You-Lin Tain
Nutrients 2023, 15(12), 2698; https://doi.org/10.3390/nu15122698 - 9 Jun 2023
Viewed by 2232
Abstract
A balanced diet during gestation is critical for fetal development, and excessive intake of saturated fats during gestation and lactation is related to an increased risk of offspring kidney disease. Emerging evidence indicates that a maternal high-fat diet influences kidney health and disease [...] Read more.
A balanced diet during gestation is critical for fetal development, and excessive intake of saturated fats during gestation and lactation is related to an increased risk of offspring kidney disease. Emerging evidence indicates that a maternal high-fat diet influences kidney health and disease of the offspring via so-called renal programming. This review summarizes preclinical research documenting the connection between a maternal high-fat diet during gestation and lactation and offspring kidney disease, as well as the molecular mechanisms behind renal programming, and early-life interventions to offset adverse programming processes. Animal models indicate that offspring kidney health can be improved via perinatal polyunsaturated fatty acid supplementation, gut microbiota changes, and modulation of nutrient-sensing signals. These findings reinforce the significance of a balanced maternal diet for the kidney health of offspring. Full article
(This article belongs to the Special Issue High-Fat Diet in High-Risk Population)
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