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Intermittent Fasting and Cardiovascular Health: Mechanisms, Benefits, and Clinical Evidence

A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Nutritional Epidemiology".

Deadline for manuscript submissions: 20 March 2026 | Viewed by 134

Special Issue Editors


E-Mail Website
Guest Editor
1. Department of Endocrinology and Nutrition, Virgen de las Nieves University Hospital, 18014 Granada, Spain
2. Biosanitary Research Institute (ibs.Granada), 18012 Madrid, Spain
3. CIBER in Physiopathology of Obesity and Nutrition (CIBEROBN), Carlos III Health Institute, 28029 Madrid, Spain
Interests: diabetes; metabolic syndrome; insulin resistance; glucose metabolism; hypertension; lipid metabolism; nutrition; clinical endocrinology; vitamin D; dietary patterns
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
1. Department of Endocrinology and Nutrition, Virgen de las Nieves University Hospital, 18014 Granada, Spain
2. Foundation for Biosanitary Research of Eastern Andalusia-Alejandro Otero (FIBAO), 18012 Granada, Spain
3. Faculty of Education, International University of La Rioja, 26006 Logroño, Spain
Interests: natural product; antioxidant; chromatography; nutritional biochemistry; redox biology; aging
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Intermittent fasting (IF) has gained significant attention as a dietary strategy with potential to improve cardiovascular health by targeting key modifiable risk factors. Unlike traditional calorie restriction, IF encompasses various eating patterns—such as time-restricted feeding, alternate-day fasting, and the 5:2 regimen—that alternate periods of eating and fasting to promote metabolic adaptation. Emerging evidence from clinical and preclinical studies suggests that IF can lower blood pressure, improve lipid profiles, enhance insulin sensitivity, reduce systemic inflammation, and support weight management, thereby addressing multiple pathways involved in the development and progression of cardiovascular disease.

This Special Issue aims to bring together cutting-edge research and comprehensive reviews exploring the role of IF in cardiovascular disease prevention and management. We particularly welcome studies investigating its effects on hypertension, dyslipidemia, obesity, type 2 diabetes, coronary artery disease, heart failure, and other cardiometabolic conditions. Contributions examining underlying molecular mechanisms—such as autophagy, oxidative stress reduction, and endothelial function improvement—as well as behavioral and adherence-related aspects are encouraged. By integrating multidisciplinary perspectives, this Special Issue seeks to clarify the clinical relevance, feasibility, and long-term safety of IF, ultimately providing evidence-based insights for its application in cardiovascular health promotion.

Dr. Araceli Muñoz-Garach
Dr. José Manuel Romero-Márquez
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nutrients is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • intermittent fasting
  • cardiovascular disease
  • cardiometabolic health
  • lipid profile
  • blood pressure
  • glycemic control
  • inflammation

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Published Papers

This special issue is now open for submission.
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