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Effects of Nutrition, Malnutrition and Excess Body Weight on Gynecological Disorders

A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Nutrition in Women".

Deadline for manuscript submissions: closed (5 October 2024) | Viewed by 11911

Special Issue Editor


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Guest Editor
Pathophysiology Unit, Department of Pathophysiology, Faculty of Medical Sciences in Katowice, The Medical University of Silesia, 40-752 Katowice, Poland
Interests: dietary recommendations; eating habits; fetus programming; gynecological disorders; malnutrition; metabolic health; nutrition; obesity; polycystic ovary syndrome (PCOS); thyroid dysfunction; women’s health
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Special Issue Information

Dear Colleagues,

Women’s health issues have been widely discussed in recent years. Chronic gynaecological disorders can affect the pubertal population, starting from precocious puberty, through hyperandrogenism with acne and hirsutism, and young-to-middle-aged women through infertility and pregnancy-related diseases, cancer, inflammatory and infectious diseases, as well as symptoms associated with menopause. The results of recent studies have undoubtedly proven that excessive caloric intake, simple carbohydrates, refined fats, and micronutrient deficiencies have the potential to initiate, exacerbate, or alleviate signs and symptoms of gynaecological disorders. Nutritional and dietary recommendations have become an integral part of the treatment of chronic conditions.

Gynaecological disorders can be accompanied by metabolic disorders, including reduced cellular insulin response, hyperglycemia, diabetes and hyperandrogenism; in addition, eating habits may exacerbate symptoms and promote the occurrence of gynaecological disorders and may affect the occurrence of metabolic disorders later in life of the foetus. Moreover, both malnutrition and excess body have been shown to cause gynaecological symptoms.

This Special Issue of Nutrients invites reviews and meta-analyses covering micronutrient supplementation, dietary recommendations, the effects of food restriction and fortification, malnutrition and obesity on the occurrence of gynaecological disorders, their course, and clinical outcomes including foetus health. It includes studies from basic research, the impact of dietary components and recommendations on the course of gynaecological disorders, health outcomes, and prognosis.

Dr. Piotr Kocełak
Guest Editor

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Keywords

  • dietary recommendations
  • eating habits
  • fetus programming
  • gynaecological disorders
  • malnutrition
  • nutrition
  • obesity
  • women’s health

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Published Papers (2 papers)

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Research

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25 pages, 1748 KiB  
Article
Effect of Tempeh and Daidzein on Calcium Status, Calcium Transporters, and Bone Metabolism Biomarkers in Ovariectomized Rats
by Iskandar Azmy Harahap, Maciej Kuligowski, Adam Cieslak, Paweł A. Kołodziejski and Joanna Suliburska
Nutrients 2024, 16(5), 651; https://doi.org/10.3390/nu16050651 - 26 Feb 2024
Cited by 5 | Viewed by 2990
Abstract
Menopause marks a critical life stage characterized by hormonal changes that significantly impact bone health, leading to a heightened susceptibility to bone fractures. This research seeks to elucidate the impact of daidzein and tempeh on calcium status, calcium transporters, and bone metabolism in [...] Read more.
Menopause marks a critical life stage characterized by hormonal changes that significantly impact bone health, leading to a heightened susceptibility to bone fractures. This research seeks to elucidate the impact of daidzein and tempeh on calcium status, calcium transporters, and bone metabolism in an ovariectomized rat model. Forty female Wistar rats, aged 3 months, participated in a two-phase experiment. The initial phase involved inducing a calcium deficit, while the second phase comprised dietary interventions across five groups: Sham (S) and Ovariectomy (O) with a standard diet, O with bisphosphonate (OB), O with pure daidzein (OD), and O with tempeh (OT). Multiple parameters, encompassing calcium levels, calcium transporters, bone histopathology, and serum bone metabolism markers, were evaluated. The findings revealed that the OT group showcased heightened levels of bone turnover markers, such as pyridinoline, C-telopeptide of type I collagen, bone alkaline phosphatase, and procollagen type I N-terminal propeptide, in contrast to S and O groups, with statistical significance (p < 0.05). Histopathologically, both the OD and OT groups exhibited effects akin to the OB group, indicating a decrease in the surface area occupied by adipocytes in the femoral bone structure, although statistically non-equivalent, supporting the directionally similar trends. Although TRPV5 and TRPV6 mRNA expression levels in the jejunum and duodenum did not display statistically significant differences (p > 0.05), the OD and OT groups exhibited increased expression compared to the O group. We hypothesized that obtained results may be related to the effect of isoflavones on estrogen pathways because of their structurally similar to endogenous estrogen and weak estrogenic properties. In conclusion, the daily consumption of pure daidzein and tempeh could potentially improve and reinstate calcium status, calcium transport, and bone metabolism in ovariectomized rats. Additionally, isoflavone products demonstrate effects similar to bisphosphonate drugs on these parameters in ovariectomized rats. Full article
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Review

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23 pages, 641 KiB  
Review
Relationships between Premenstrual Syndrome (PMS) and Diet Composition, Dietary Patterns and Eating Behaviors
by Paulina Oboza, Natalia Ogarek, Mariusz Wójtowicz, Tahar Ben Rhaiem, Magdalena Olszanecka-Glinianowicz and Piotr Kocełak
Nutrients 2024, 16(12), 1911; https://doi.org/10.3390/nu16121911 - 17 Jun 2024
Cited by 7 | Viewed by 8328
Abstract
Premenstrual Syndrome (PMS) is a disorder between gynecology and psychiatry which includes cognitive, affective, and somatic symptoms from mild to severe. The most severe form of PMS is premenstrual dysphoric disorder (PMDD) and it is considered a form of depressive disorder. An association [...] Read more.
Premenstrual Syndrome (PMS) is a disorder between gynecology and psychiatry which includes cognitive, affective, and somatic symptoms from mild to severe. The most severe form of PMS is premenstrual dysphoric disorder (PMDD) and it is considered a form of depressive disorder. An association between diet composition and the occurrence of PMS and its severity have been suggested. As such, this manuscript discusses the relationships between diet composition, dietary patterns and eating behaviors, and PMS. PubMed, Embase, Cochrane, and Web of Science databases were searched for related studies up to 18 January 2024. A text search with the following keywords singly or in combination was conducted: “Premenstrual syndrome”, “Nutrition”, “Diet composition”, “Dietary patterns”, and “Eating behaviors”. Studies published so far showed that low intake of simple carbohydrates, fats, salt, and alcohol, and high of fresh, unprocessed foods rich in B vitamins, vitamin D, zinc, calcium, and omega-3 fatty acids may help prevent the onset of PMS and reduce the severity of its symptoms. However, further studies are needed to formulate definitive recommendations for the use of vitamins, micronutrients and other dietary ingredients supplementation in women with PMS to improve functioning, overall well-being, and physical health. Large, randomized, double-blind clinical trials across diverse populations are necessary to formulate clear recommendations for supplementation in women with PMS. Full article
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