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Nutritional Intervention for Pediatric Allergy and Asthma

A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Pediatric Nutrition".

Deadline for manuscript submissions: 15 November 2025 | Viewed by 1023

Special Issue Editor


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Guest Editor
Department of Clinical Science and Education, Stockholm South General Hospital, Karolinska Institutet, 11883 Solna, Sweden
Interests: asthma; food allergy; immunomodulation; pediatric nutrition

Special Issue Information

Dear Colleagues,

Nutritional factors have been associated with asthma and allergy development as well as with disease control. To prevent food allergies, there seems to be an important window of opportunity in infancy where the introduction of allergenic foods has the potential to affect allergy development. Treatment of food allergy has shifted from only avoidance towards interventions aiming at desensitization and tolerance. In asthma prevention, nutritional intervention during pregnancy has been successful but proven to be more pronounced in specific sub-groups. There is no known optimal diet during childhood to improve disease control, but recommendations include increased diet diversity and improved diet quality.

Dietary intake is modifiable, inexpensive, and has the potential to improve quality of life as well as prevent disease development. This Special Issue aims to highlight recent progress and current issues related to nutritional interventions that prevent and treat pediatric allergy and asthma. We are pleased to invite you to contribute.

Articles that shed light on mechanisms of action, windows of opportunity, specific populations to target, and interaction between nutritional components are welcome. Authors are also welcome to submit research and reviews that highlight beneficial supplements and diets as well as food to avoid.

We look forward to receiving your contributions.

Dr. Susanna Klevebro
Guest Editor

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Keywords

  • allergy
  • asthma
  • inflammation
  • immunology
  • diet
  • pediatric nutrition
  • supplement
  • food allergy
  • allergic rhinitis
  • atopic dermatitis

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Published Papers (1 paper)

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Research

13 pages, 242 KiB  
Article
The Impact of Dietary Counseling on the Nutritional Status of Pediatric Patients with Non-IgE-Mediated Gastrointestinal Food Allergies: A Non-Randomized, Prospective Intervention Study
by Serena Coppola, Laura Carucci, Alessandra Agizza, Rita Nocerino, Rosilenia Carandente, Maria Francesca Catalano and Roberto Berni Canani
Nutrients 2025, 17(6), 1080; https://doi.org/10.3390/nu17061080 - 19 Mar 2025
Viewed by 801
Abstract
Background/Objectives: Pediatric patients with non-IgE-mediated gastrointestinal food allergies (non-IgE-GIFAs) may experience alterations of nutritional status. This non-randomized, prospective intervention study investigated the impact of dietary counseling on nutritional status in pediatric patients with non-IgE-GIFAs. Methods: Patients of both sexes aged 0–14 [...] Read more.
Background/Objectives: Pediatric patients with non-IgE-mediated gastrointestinal food allergies (non-IgE-GIFAs) may experience alterations of nutritional status. This non-randomized, prospective intervention study investigated the impact of dietary counseling on nutritional status in pediatric patients with non-IgE-GIFAs. Methods: Patients of both sexes aged 0–14 years newly diagnosed with non-IgE-GIFAs received dietary counseling provided by certified pediatric dietitians immediately after diagnosis. Nutritional status parameters were assessed to identify nutritional status alterations at baseline and after 12 months of intervention (T12). Results: The study included 100 patients (58% male, mean age 8.5 ± 8.8 months). Non-IgE-GIFAs phenotypes included food protein-induced enteropathy (FPE, 44%), food protein-induced enterocolitis syndrome (FPIES, 11%), food protein-induced allergic proctocolitis (FPIAP, 17%), and food protein-induced motility disorders (FPIMD, 28%). At diagnosis, 1% was affected by obesity (1 FPIAP), 5% were affected by overweight (2 FPE, 1 FPIAP, and 2 FPIMD), 7% were moderately underweight (5 FPE and 2 FPIMD), 1% was severely underweight (1 FPE), 7% were moderately stunted (4 FPE, 1 FPIAP, and 2 FPIMD), 16% were moderately wasted (11 FPE, 1 FPIES, 1 FPIAP, and 3 FPIMD), and 4% were severely wasted (2 FPE and 2 FPIMD). At T12, improvements in anthropometric parameters were observed, along with a reduction in the prevalence of malnutrition by excess (6% at diagnosis vs. 2% at T12) and a reduction in the undernutrition subtypes rate, including underweight, stunting, and wasting (26% at diagnosis vs. 3% at T12, p < 0.001). Conclusions: Non-IgE-GIFAs can negatively impact the nutritional status of pediatric patients. Thus, dietary counseling could be an effective strategy for preventing and managing nutritional alterations in these patients. Full article
(This article belongs to the Special Issue Nutritional Intervention for Pediatric Allergy and Asthma)
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