Dietary Effects on Gene Expression and Metabolic Profiles
A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Nutrigenetics and Nutrigenomics".
Deadline for manuscript submissions: closed (15 September 2025) | Viewed by 2573
Special Issue Editors
Interests: metabolic diseases; molecular biology; inflammation; oxidative stress; antioxidants; dietary bioactive compounds; diabetes mellitus; oligonucleotides
Special Issue Information
Dear Colleagues,
Compelling evidence indicates that components in diet regulate gene expression, cellular metabolic homeostasis, and the overall functioning of an organism, acting through a variety of molecular mechanisms. The type of dietary pattern an individual consumes is considered to be one of the most important modifiable risk factors in many different diet-dependent diseases, such as overweight/obesity, cardiovascular diseases, diabetes mellitus, certain cancers, and osteoporosis. However, genetic variations, including SNPs (single-nucleotide polymorphisms), may also affect dietary-mediated dysfunctions such as the dysregulation of metabolism; therefore, SNP analysis has proven to be a powerful molecular tool for determining nutrients’ impact on human health. Additionally, advances in so-called omics technologies have enhanced our ability to deeply characterize the complex biological processes underlying the effects of dietary patterns/bioactive diet components on human health.
This Special Issue welcomes original articles, literature reviews, and meta-analyses that contribute to our understanding of how the intake of different dietary patterns or single bioactive compounds of plant and animal origin can impact gene responses, metabolic processes, as well as cellular functions in physiology and diet-dependent diseases. Studies applying omics strategies to identify the complex biological mechanisms underlying the influence of food components on health are encouraged since these advanced technologies have become essential tools in nutrition research that can help in the preparation of personalized diets in order to prevent or support treatments of diseases. Topics of interest also include studies evaluating the potential associations of SNPs with dietary intake in individuals with different ethnic backgrounds.
Dr. Marzena Wójcik
Dr. Andrzej Zieleniak
Guest Editors
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Keywords
- bioactive compounds
- dietary patterns
- diet-dependent diseases
- gene expression
- molecular mechanisms of action
- macronutrient composition
- micronutrients
- omics
- personalized nutrition
- SNPs
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