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The Role of Diet in Osteoporosis—Prevention and Management

A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Nutrition and Public Health".

Deadline for manuscript submissions: closed (31 July 2024) | Viewed by 2195

Special Issue Editor


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Guest Editor
College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea
Interests: bone metabolism; rare bone disease; secondary osteoporosis; osteoporosis prevention; osteoporosis treatment

Special Issue Information

Dear Colleagues,

I am honored to introduce you to a Special Issue dedicated to the pressing issue of osteoporosis. This chronic ailment warrants sustained attention and management, especially given its escalating global prevalence. The gravity of osteoporotic fractures further highlights the importance of maintaining long-term vigilance towards this disease.

Recent advances in osteoporosis treatment have been promising, leading to enhanced patient outcomes. Nevertheless, the role of a healthful lifestyle, in parallel with medication, remains paramount in both osteoporosis prevention and treatment. Specifically, an appropriate dietary regimen not only has the potential to stave off osteoporosis, but could also augment treatment efficacy and play an instrumental role in bone metabolism. Given this fact, numerous studies are currently investigating the dietary means of enabling osteoporosis prevention and treatment.

The scope of this Special Issue is 'The Role of Diet in Osteoporosis - Prevention and Management'. We invite researchers to submit publications discussing the diverse ways that diet can aid in osteoporosis prevention and management, with an emphasis on treating diet as a primary source of bone metabolism-essential minerals, such as calcium and vitamins. We are eager to entertain a breadth of diet-centric studies relevant to bone metabolism. Our objective is to facilitate a comprehensive exchange in the most recent insights into the nexus between diet and bone metabolism, drawing on evidence included in both review articles and original research papers.

Dr. Jeonghoon Ha
Guest Editor

Manuscript Submission Information

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Keywords

  • osteoporosis
  • fracture
  • bone
  • diet
  • calcium
  • vitamin D
  • diet
  • food
  • nutrition

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Published Papers (1 paper)

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Research

14 pages, 752 KiB  
Article
Comparative Analysis of Myokines and Bone Metabolism Markers in Prepubertal Vegetarian and Omnivorous Children
by Jadwiga Ambroszkiewicz, Joanna Gajewska, Katarzyna Szamotulska, Grażyna Rowicka, Witold Klemarczyk, Małgorzata Strucińska and Magdalena Chełchowska
Nutrients 2024, 16(13), 2009; https://doi.org/10.3390/nu16132009 - 25 Jun 2024
Cited by 1 | Viewed by 1651
Abstract
The role of bone and muscle as endocrine organs may be important contributing factors for children’s growth and development. Myokines, secreted by muscle cells, play a role in regulating bone metabolism, either directly or indirectly. Conversely, markers of bone metabolism, reflecting the balance [...] Read more.
The role of bone and muscle as endocrine organs may be important contributing factors for children’s growth and development. Myokines, secreted by muscle cells, play a role in regulating bone metabolism, either directly or indirectly. Conversely, markers of bone metabolism, reflecting the balance between bone formation and bone resorption, can also influence myokine secretion. This study investigated a panel of serum myokines and their relationships with bone metabolism markers in children following vegetarian and omnivorous diets. A cohort of sixty-eight healthy prepubertal children, comprising 44 vegetarians and 24 omnivores, participated in this study. Anthropometric measurements, dietary assessments, and biochemical analyses were conducted. To evaluate the serum concentrations of bone markers and myokines, an enzyme-linked immunosorbent assay (ELISA) was used. The studied children did not differ regarding their serum myokine levels, except for a higher concentration of decorin in the vegetarian group (p = 0.020). The vegetarians demonstrated distinct pattern of bone metabolism markers compared to the omnivores, with lower levels of N-terminal propeptide of type I procollagen (P1NP) (p = 0.001) and elevated levels of C-terminal telopeptide of type I collagen (CTX-I) (p = 0.018). Consequently, the P1NP/CTX-I ratio was significantly decreased in the vegetarians. The children following a vegetarian diet showed impaired bone metabolism with reduced bone formation and increased bone resorption. Higher levels of decorin, a myokine involved in collagen fibrillogenesis and essential for tissue structure and function, may suggest a potential compensatory mechanism contributing to maintaining bone homeostasis in vegetarians. The observed significant positive correlations between myostatin and bone metabolism markers, including P1NP and soluble receptor activator of nuclear factor kappa-B ligand (sRANKL), suggest an interplay between muscle and bone metabolism, potentially through the RANK/RANKL/OPG signaling pathway. Full article
(This article belongs to the Special Issue The Role of Diet in Osteoporosis—Prevention and Management)
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