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Mediterranean Diet in Human Health and Disease

A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Nutritional Epidemiology".

Deadline for manuscript submissions: closed (25 May 2024) | Viewed by 2888

Special Issue Editor


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Guest Editor
Clinical and Health Sciences, Alliance for Research in Exercise, Nutrition and Activity (ARENA), University of South Australia, GPO Box 2471, Adelaide, SA 5001, Australia
Interests: Mediterranean diet; lipids, fatty acids; omega-3 fatty acids; dairy foods; antioxidants; dietary flavonoids; cardiovascular disease dementia risk; cognitive performance; psychological wellbeing
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The Mediterranean diet is the traditional diet of many countries surrounding the Mediterranean basin. It emphasises the consumption of fruit and vegetables, wholegrains, oily fish, legumes and nuts, extra-virgin olive oil and moderate amounts of dairy foods and white meat, and low amounts of red and processed meats as well as discretionary foods. Red wine is enjoyed moderately, socially, and with meals.

Adherence to the Mediterranean diet is linked with a reduced risk of several chronic diseases and promotes wellbeing and healthy ageing. It may be a less expensive diet than other diets such as the Western diet and environmentally sustainable.

In this Special Issue, we aim to provide new insights into the Mediterranean diet and human health, and we encourage authors to submit their research or reviews that will help to better elucidate this area of research.

Dr. Karen Murphy
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

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Keywords

  • randomised controlled trials
  • extra virgin olive oil
  • Mediterranean diet
  • health

Published Papers (1 paper)

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Review

20 pages, 1215 KiB  
Review
Olive Oil Components as Novel Antioxidants in Neuroblastoma Treatment: Exploring the Therapeutic Potential of Oleuropein and Hydroxytyrosol
by Marta Gonçalves, Anna Aiello, María Rodríguez-Pérez, Giulia Accardi, Emma Burgos-Ramos and Paula Silva
Nutrients 2024, 16(6), 818; https://doi.org/10.3390/nu16060818 - 13 Mar 2024
Viewed by 2660
Abstract
In this review, we explored the therapeutic potential of oleuropein (OLE) and hydroxytyrosol (HT) in the treatment of neuroblastoma (NB). NB is an extracranial tumour that predominantly affects children aged between 17 and 18 months. Recurrence and drug resistance have emerged as the [...] Read more.
In this review, we explored the therapeutic potential of oleuropein (OLE) and hydroxytyrosol (HT) in the treatment of neuroblastoma (NB). NB is an extracranial tumour that predominantly affects children aged between 17 and 18 months. Recurrence and drug resistance have emerged as the biggest challenges when treating NB, leading to a crucial need for new therapeutic approaches. Food of the Mediterranean Diet (MD) presents several health benefits, including that of cancer treatment. In this review, we emphasised olive oil since it is one of the main liquid ingredients of the MD. OLE is the principal phenolic compound that constitutes olive oil and is hydrolysed to produce HT. Considering that tumour cells produce increased amounts of reactive oxygen species, this review highlights the antioxidant properties of OLE and HT and how they could result in increased cellular antioxidant defences and reduced oxidative damage in NB cells. Moreover, we highlight that these phenolic compounds lead to apoptosis and cell cycle arrest, reduce the side effects caused by conventional treatments, and activate tumours that become dormant as a resistance mechanism. Future research should explore the effects of these compounds and other antioxidants on the treatment of NB in vivo. Full article
(This article belongs to the Special Issue Mediterranean Diet in Human Health and Disease)
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