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Nutrition and Lifestyle Influences on Age-Related Frailty and Sarcopenia

A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Geriatric Nutrition".

Deadline for manuscript submissions: 15 October 2025 | Viewed by 35

Special Issue Editor


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Guest Editor
1. Internal Medicine Unit, IRCCS San Raffaele Scientific Institute, 20132 Milan, Italy
2. Division of Immunology, Transplantation and Infectious Diseases, Vita-Salute San Raffaele University, 20100 Milan, Italy
Interests: frailty; respiratory dysfunction; sarcopenia; geriatrics
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Aging is associated with an increased risk of frailty and sarcopenia, conditions that significantly impact mobility, independence, and overall quality of life. Emerging evidence suggests that nutrition and lifestyle factors play a crucial role in mitigating these conditions, offering potential strategies for prevention and management.

This Special Issue of Nutrients aims to explore the complex interplay between diet, physical activity, and other lifestyle behaviors in relation to frailty and sarcopenia in aging populations. We welcome original research articles, systematic reviews, and meta-analyses that investigate key topics, including (but not limited to) the following:

  • The role of protein intake, amino acid supplementation, and dietary patterns in muscle mass preservation.
  • The impact of micronutrients, antioxidants, and anti-inflammatory diets on sarcopenia progression.
  • Lifestyle interventions combining nutrition, exercise, and behavioral strategies to prevent frailty.
  • The gut–muscle axis and the influence of the microbiome on muscle health.
  • The effects of intermittent fasting, caloric restriction, and other dietary approaches on muscle function.

This Special Issue provides a platform for advancing scientific understanding and translating research into practical recommendations for healthy aging. We look forward to receiving your contributions to this important area of research.

Dr. Sarah Damanti
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nutrients is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • frailty
  • sarcopenia
  • aging
  • nutrition
  • dietary interventions
  • muscle health
  • protein intake
  • physical activity
  • gut–muscle axis
  • lifestyle factors

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Published Papers

This special issue is now open for submission.
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