Association of the Microbiota with Neurodegenerative Diseases
A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Prebiotics and Probiotics".
Deadline for manuscript submissions: closed (15 April 2025) | Viewed by 3363
Special Issue Editor
Interests: Alzheimer’s disease; Parkinson’s disease; circadian rhythms; alcohol-induced tissue damage; microbiome; intestine-derived inflammation; post-traumatic stress disorder
Special Issue Information
Dear Colleagues
This Special Issue of Nutrients will explore the microbiota–gut–brain axis and the implications for neurodegenerative disease. Articles in this issue will delve into the complex interplay between the microbiota (intestinal, oral, nasal) and the central nervous system, examining how alterations in gut microbiota composition and function may influence neurodegenerative disease. Articles will investigate (1) the following mechanisms: how the microbiota influences neuroinflammation, the immune system, and the production of neuroactive metabolites that influence brain health, (2) disease-specific dysbiosis: the characteristic changes in gut microbiota profiles associated with different neurodegenerative diseases, (3) lifestyle and environment modulation: how modifiable factors can influence the microbiome and disease risk and progression, (4) dietary modulation: the role of nutrition in shaping the gut microbiota and its potential to modify disease risk and progression, and (5) therapeutic strategies: emerging interventions targeting the gut microbiota, including prebiotics, probiotics, postbiotics, and fecal microbiota transplantation, as novel approaches for preventing or treating neurodegenerative disease. This collection will provide a better understanding of the current state of knowledge and highlight promising avenues for research into the microbiota as a key player in neurodegenerative disease
Dr. Robin M. Voigt-Zuwala
Guest Editor
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Keywords
- microbiota
- microbiota metabolites
- gut–brain axis
- microbiota–gut–brain axis
- neurodegenerative disease
- Alzheimer’s disease
- dementia
- Parkinson’s disease
- Huntington’s disease
- amylotrophic lateral sclerosis
- multiple sclerosis
- immune system
- neuroinflammation
- microbiota-tageted therapeutics
- diet-induced effects on the microbiome
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